Nature Search

Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

Patricia Dauer
Vineet K. Gupta
Sulagna Banerjee
ResearchOpen Access08 May 2017
Scientific Reports

Volume: 7, P: 1-9
Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity

The anti-tumour immune response greatly depends on the number of tumour neoantigens. Here the authors show in mouse models that a therapeutic strategy aimed at increasing the number of neoantigens via downregulating TAP, an antigen processing associated protein, enhances anti-tumour immunity and the efficacy of immunotherapy.

Greta Garrido
Brett Schrand
Eli Gilboa
ResearchOpen Access21 Aug 2019
Nature Communications

Volume: 10, P: 1-13
The war against pancreatic cancer in 2020 — advances on all fronts

In 2020, important advances were made across three major frontiers of pancreatic ductal adenocarcinoma (PDAC) research: risk factors, therapeutic resistance and tumour recurrence. Pathophysiology of obesity-mediated PDAC initiation was elucidated, novel stromal mechanisms of therapeutic resistance were unveiled and the genetic evolution of recurrent PDAC under therapeutic pressures was tracked in human samples.

Tejeshwar Jain
Vikas Dudeja
News & Views07 Jan 2021
Nature Reviews Gastroenterology & Hepatology

Volume: 18, P: 99-100
Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer

Alice Nomura
Kaustav Majumder
Ashok K Saluja
Research24 Oct 2016
Laboratory Investigation

Volume: 96, P: 1268-1278
SeeTB: A novel alternative to sputum smear microscopy to diagnose tuberculosis in high burden countries

Vikas Pandey
Pooja Singh
Seyed E. Hasnain
ResearchOpen Access12 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness”

Patricia Dauer
Nikita S. Sharma
Sulagna Banerjee
ResearchOpen Access12 Feb 2019
Cell Death & Disease

Volume: 10, P: 1-13
Long non-coding RNA GAS5 acts as proliferation “brakes” in CD133+ cells responsible for tumor recurrence

Nikita S. Sharma
Prisca Gnamlin
Sulagna Banerjee
ResearchOpen Access18 Nov 2019
Oncogenesis

Volume: 8, P: 1-13
Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

Olivia McGinn
Vineet K. Gupta
Sulagna Banerjee
ResearchOpen Access11 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F

Amanda R Oliveira
Georg Beyer
Vikas Dudeja
Research20 Apr 2015
Laboratory Investigation

Volume: 95, P: 648-659

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