In this work, authors present genetic and atomic insights of the Mycobacterium abscessus cytochrome bcc:aa3, enabling the design of ND-011458 as a potent QcrB inhibitor, with the inhibitor bound enzyme structure paving the way for the development of a lead compound.
- Vikneswaran Mathiyazakan
- Emilia Xin Yi Tan
- Gerhard Grüber
