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Anti-CD19 CAR T cells for pediatric patients with treatment-refractory autoimmune diseases

In a case series of eight pediatric patients with systemic lupus erythematosus, dermatomyositis or systemic sclerosis, autologous anti-CD19 CAR T cell therapy was feasible, safe and effective in reducing disease activity.

Marco Becilli
Markus Metzler
Franco Locatelli
Research05 Feb 2026
Nature Medicine

P: 1-13

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Anti-CD19 CAR T cells for pediatric patients with treatment-refractory autoimmune diseases

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