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Advanced filters: Author: Virginie Janssens Clear advanced filters

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

In mouse and human squamous cell carcinoma, loss of function of FAT1 promotes tumour initiation, malignant progression and metastasis through the activation of a hybrid epithelial-to-mesenchymal transition phenotype.

Ievgenia Pastushenko
Federico Mauri
Cédric Blanpain
Research16 Dec 2020
Nature

Volume: 589, P: 448-455
Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2

Manuel Johanns
Pascale Lemoine
Patrick Henriet
ResearchOpen Access28 Jun 2017
Scientific Reports

Volume: 7, P: 1-8
Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency

Giuseppina Grieco
Virginie Janssens
Pierre J. Courtoy
ResearchOpen Access20 Sept 2018
Scientific Reports

Volume: 8, P: 1-16