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Showing 1–4 of 4 results
Advanced filters: Author: Vishwajeet Puri Clear advanced filters

  • Adipose tissue controls whole-body lipid flux, thereby modulating both glucose and lipid homeostasis in humans. Discovery of new targets that regulate fatty acids in adipocytes might lead to therapeutic modalities that can prevent insulin resistance and type 2 diabetes.

    • Adilson Guilherme
    • Joseph V. Virbasius
    • Michael P. Czech
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 9, P: 367-377

  • This Review provides an up-to-date overview of the lipolytic effects of growth hormone (GH), setting current knowledge into the context of historical data. In addition, the molecular mechanisms of GH-induced lipolysis and insulin resistance as well as the actions of GH on different adipose tissue depots and adipocyte subsets are discussed.

    • John J. Kopchick
    • Darlene E. Berryman
    • Jens O. L. Jorgensen
    Reviews
    Nature Reviews Endocrinology
    Volume: 16, P: 135-146

  • The actions of growth hormone (GH) on growth and many other processes are well-described. This Review highlights clinical data from patients with acromegaly or GH deficiency, alongside data from cellular and animal studies, to reveal novel actions of GH in fibrosis, cardiovascular function and cancer.

    • John J. Kopchick
    • Reetobrata Basu
    • Vishwajeet Puri
    Reviews
    Nature Reviews Endocrinology
    Volume: 18, P: 558-573