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Leukemia (26)
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Showing 1–44 of 44 results

Advanced filters: Author: W Vainchenker Clear advanced filters

Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines

F Goncalves
C Lacout
D Duménil
Research02 Sept 1998
Leukemia

Volume: 12, P: 1355-1366
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

Kenneth Kaushansky
Si Lok
Donald C. Foster
Research16 Jun 1994
Nature

Volume: 369, P: 568-571
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

Si Lok
Kenneth Kaushansky
Donald C. Foster
Research16 Jun 1994
Nature

Volume: 369, P: 565-568
Human hematopoietic progenitor cell isolation based on galactose-specific cell surface binding

George G. Pipia
Michael W. Long
Research01 Oct 1997
Nature Biotechnology

Volume: 15, P: 1007-1011
Elucidation of gene function using C-5 propyne antisense oligonucleotides

W. Michael Flanagan
Leon L. Su
Richard W. Wagner
Research01 Sept 1996
Nature Biotechnology

Volume: 14, P: 1139-1145
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

Single-cell multi-omic analyses show that chronic inflammation contributes to myeloproliferative neoplasm transformation to secondary acute myeloid leukemia by enhancing tumor protein 53 (TP53) mutant cell fitness and genetic evolution.

Alba Rodriguez-Meira
Ruggiero Norfo
Adam J. Mead
ResearchOpen Access04 Sept 2023
Nature Genetics

Volume: 55, P: 1531-1541
Megakaryocyte growth and development factor (MGDF)-induced acute leukemia cell proliferation and clonal growth is associated with functional c-mpl

W Piacibello
F Sanavio
L Pegoraro
Research01 Apr 1997
Leukemia

Volume: 11, P: 531-540
Defective Production of Interleukin-6 by Monocytes: A Possible Mechanism Underlying Several Host Defense Deficiencies of Neonates

Kurt R Schibler
Kenneth W Liechty
Robert D Christensen
Research01 Jan 1992
Pediatric Research

Volume: 31, P: 18-21
In vitro and in vivo evaluation of the haematopoietic potential of skeletal muscle in a non-human primate model

C Haond
M Drouet
F Herodin
Research26 Nov 2007
Bone Marrow Transplantation

Volume: 41, P: 579-584
Rapid generation of a tetracycline-inducible BCR-ABL defective retrovirus using a single autoregulatory retroviral cassette

A Dugray
JF Geay
AG Turhan
Research04 Oct 2001
Leukemia

Volume: 15, P: 1658-1662
Use of the 46/1 haplotype to model JAK2^V617F clonal architecture in PV patients: clonal evolution and impact of IFNα treatment

S Hasan
B Cassinat
I Plo
Correspondence22 Oct 2013
Leukemia

Volume: 28, P: 460-463
Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms

A Ali
O Bluteau
N Debili
ResearchOpen Access25 Jul 2013
Cell Death & Disease

Volume: 4, P: e738
Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro

H Moniz
M Gastou
L Da Costa
ResearchOpen Access26 Jul 2012
Cell Death & Disease

Volume: 3, P: e356
Major effects of TPO delivered by a single injection of a recombinant adenovirus on prevention of septicemia and anemia associated with myelosuppression in mice: risk of sustained expression inducing myelofibrosis due to immunosuppression

MA Abina
M Tulliez
H Haddada
Research30 Apr 1998
Gene Therapy

Volume: 5, P: 497-506
New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G₁/S-phase transition

R Chaligné
C Tonetti
S Giraudier
Research05 Jun 2008
Leukemia

Volume: 22, P: 1557-1566
The serum response factor (SRF)/megakaryocytic acute leukemia (MAL) network participates in megakaryocyte development

C Ragu
S Boukour
V Penard-Lacronique
Correspondence29 Apr 2010
Leukemia

Volume: 24, P: 1227-1230
Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution

X Cabagnols
J P Defour
O Bluteau
Correspondence12 Sept 2014
Leukemia

Volume: 29, P: 249-252
Does increasing the JAK2V617F assay sensitivity allow to identify more patients with MPN?

E Kouroupi
J-J Kiladjian
B Cassinat
CorrespondenceOpen Access04 May 2012
Blood Cancer Journal

Volume: 2, P: e70
Alterations of NFIA in chronic malignant myeloid diseases

F Bernard
V Gelsi-Boyer
D Birnbaum
Correspondence28 Aug 2008
Leukemia

Volume: 23, P: 583-585
Oncogenic kinases of myeloproliferative disorders induce both protein synthesis and G1 activators

H Lelièvre
N Cervera
D Birnbaum
Correspondence10 Aug 2006
Leukemia

Volume: 20, P: 1885-1888
SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis

R Chaligné
C Tonetti
S Giraudier
Correspondence19 Feb 2009
Leukemia

Volume: 23, P: 1186-1190
Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin

T Balligand
Y Achouri
S N Constantinescu
Correspondence29 Feb 2016
Leukemia

Volume: 30, P: 1775-1778
Myelofibrosis, JAK2 inhibitors and erythropoiesis

W Vainchenker
F Favale
Editorial05 Jun 2013
Leukemia

Volume: 27, P: 1219-1223
Clonal analysis of erythroid progenitors suggests that pegylated interferon α-2a treatment targets JAK2^V617F clones without affecting TET2 mutant cells

J-J Kiladjian
A Massé
F Delhommeau
Correspondence03 Jun 2010
Leukemia

Volume: 24, P: 1519-1523
Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis

C James
F Delhommeau
N Casadevall
Correspondence08 Dec 2005
Leukemia

Volume: 20, P: 350-353
Thrombopoietin receptor is required for the oncogenic function of CALR mutants

H Nivarthi
D Chen
R Kralovics
CorrespondenceOpen Access17 Feb 2016
Leukemia

Volume: 30, P: 1759-1763
Mutations of ASXL1 gene in myeloproliferative neoplasms

N Carbuccia
A Murati
M J Mozziconacci
Correspondence16 Jul 2009
Leukemia

Volume: 23, P: 2183-2186
Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling

A-S Gabet
S Coulon
G Courtois
Research12 Nov 2010
Cell Death & Differentiation

Volume: 18, P: 678-689
Membrane-bound Delta-4 Notch ligand reduces the proliferative activity of primitive human hematopoietic CD34⁺CD38^low cells while maintaining their LTC-IC potential

E Lauret
C Catelain
A Bennaceur-Griscelli
Research26 Feb 2004
Leukemia

Volume: 18, P: 788-797
JAK2^V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

M Nakatake
B Monte-Mor
I Plo
Research25 Jul 2011
Oncogene

Volume: 31, P: 1323-1333
Biological effects induced by variable levels of BCR-ABL protein in the pluripotent hematopoietic cell line UT-7

C Issaad
M Ahmed
AG Turhan
Research03 Apr 2000
Leukemia

Volume: 14, P: 662-670
A lentiviral vector encoding the human Wiskott–Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice

S Charrier
D Stockholm
A Galy
Research16 Dec 2004
Gene Therapy

Volume: 12, P: 597-606
Constitutive JunB expression, associated with the JAK2 V617F mutation, stimulates proliferation of the erythroid lineage

B da Costa Reis Monte-Mór
I Plo
F F Costa
Research09 Oct 2008
Leukemia

Volume: 23, P: 144-152
A role for reactive oxygen species in JAK2^V617F myeloproliferative neoplasm progression

C Marty
C Lacout
I Plo
Research05 Apr 2013
Leukemia

Volume: 27, P: 2187-2195
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

A Tefferi
A Pardanani
R L Levine
Research05 Mar 2009
Leukemia

Volume: 23, P: 905-911
Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

M Girardot
C Pecquet
S N Constantinescu
Research31 Mar 2014
Oncogene

Volume: 34, P: 1323-1332
JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma

A Bouchekioua
L Scourzic
P Coppo
Research21 May 2013
Leukemia

Volume: 28, P: 338-348
p210^BCR-ABL reprograms transformed and normal human megakaryocytic progenitor cells into erythroid cells and suppresses FLI-1 transcription

D Buet
H Raslova
F Louache
Research22 Feb 2007
Leukemia

Volume: 21, P: 917-925
CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model

Y Zhang
S Patel
F Louache
ResearchOpen Access04 Oct 2012
Cell Death & Disease

Volume: 3, P: e396
BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features

N C P Cross
G Q Daley
J M Goldman
Editorial12 Nov 2008
Leukemia

Volume: 22, P: 1975-1989
The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

E Solary
O A Bernard
W Vainchenker
Reviews13 Nov 2013
Leukemia

Volume: 28, P: 485-496
JAK/STAT signaling in hematological malignancies

W Vainchenker
S N Constantinescu
Reviews06 Aug 2012
Oncogene

Volume: 32, P: 2601-2613
Miscreant myeloproliferative disorder stem cells

C H M Jamieson
C F Barroga
W P Vainchenker
Reviews16 Oct 2008
Leukemia

Volume: 22, P: 2011-2019
Quantification of lentiviral vector copy numbers in individual hematopoietic colony-forming cells shows vector dose-dependent effects on the frequency and level of transduction

S Charrier
M Ferrand
A Galy
ResearchOpen Access16 Dec 2010
Gene Therapy

Volume: 18, P: 479-487