Kathiriya et al. identify a cardiac progenitor lineage with expression of Tbx5 and anterior heart field-specific expression of Mef2c that bisects the intraventricular septum during development and show that alterations in this lineage lead to congenital heart defects in mice.
- Irfan S. Kathiriya
- Martin H. Dominguez
- Benoit G. Bruneau