B cells are unique in their ability to link the innate and adaptive immune systems owing to their expression of both an antigen-specific B cell receptor (BCR) and pattern-recognizing Toll-like receptors (TLRs). This article focuses on the role of dual BCR and TLR signalling in fine-tuning B cell responses, with a particular emphasis on B cell-intrinsic events.
- David J. Rawlings
- Marc A. Schwartz
- Almut Meyer-Bahlburg
