Nature Search

Functional divergence and intron variability during evolution of angiosperm TERMINAL FLOWER1 (TFL1) genes

Jian Gao
Bing-Hong Huang
Pei-Chun Liao
ResearchOpen Access01 Nov 2017
Scientific Reports

Volume: 7, P: 1-13
Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger

The ClC-3 chloride/proton exchanger is both physiologically and pathologically critical. Here, authors determined the structures of wildtype and disease-causing I607T mutant of ClC-3 in the apo and adenine nucleotides bounded states, which lays the structural basis of adenine nucleotides regulation in ClC-3.

Yangzhuoqun Wan
Shuangshuang Guo
Fan Yang
ResearchOpen Access06 Aug 2024
Nature Communications

Volume: 15, P: 1-13
The Geminga supernova as a possible cause of the local interstellar bubble

Neil Gehrels
Wan Chen
Research25 Feb 1993
Nature

Volume: 361, P: 706-707
Increased CO₂ fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast

CO₂ fixation plays an important role to make bioproduction cost competitive. Here, the authors take 3-hydroxypropionic acid as an example to showcase how to achieve high carbon yield production through increasing the accessible bicarbonate, minimizing native CO₂ release and avoiding carbon waste.

Ning Qin
Lingyun Li
Zihe Liu
ResearchOpen Access21 Feb 2024
Nature Communications

Volume: 15, P: 1-15
Comparative effects of 10-Hz rTMS and iTBS on cortico-striatal connectivity in major depressive disorder: a sham-controlled study

Cheng-Ta Li
Wan-Chen Chang
Pei-Chi Tu
Research28 Jun 2025
Molecular Psychiatry

Volume: 30, P: 5084-5092
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

Adipogenesis associated Mth938 Domain Containing gene (AAMDC) is frequently amplified in the IntClus2 subgroup of ER + breast cancer. Here, the authors show that AAMDC drives tumourigenesis through activating PI3K-AKT-mTOR pathway for metabolic reprogramming.

Emily Golden
Rabab Rashwan
Pilar Blancafort
ResearchOpen Access26 Mar 2021
Nature Communications

Volume: 12, P: 1-22
Fusion of circulant singular spectrum analysis and multiscale local ternary patterns for effective spectral-spatial feature extraction and small sample hyperspectral image classification

Xiaoqing Wan
Feng Chen
Hui Liu
ResearchOpen Access26 Feb 2025
Scientific Reports

Volume: 15, P: 1-21
A community effort to optimize sequence-based deep learning models of gene regulation

A benchmarking competition improves tools that predict how regulatory regions control gene expression.

Abdul Muntakim Rafi
Daria Nogina
Carl G. de Boer
ResearchOpen Access11 Oct 2024
Nature Biotechnology

Volume: 43, P: 1373-1383
A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant

The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, and protection from challenge (Omicron and Delta) in various animal models.

Cai He
Jingyun Yang
Xiawei Wei
ResearchOpen Access17 Sept 2022
Nature Communications

Volume: 13, P: 1-14
Recurrent chromosome reshuffling and the evolution of neo-sex chromosomes in parrots

Parrots have undergone substantial karyotype evolution compared to most other birds. Here, Huang et al. analyze chromosome-level genome assemblies for four parrot species and elucidate the complex evolutionary history of parrot chromosomes.

Zhen Huang
Ivanete De O. Furo
Luohao Xu
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-11
Sketched oxide single-electron transistor

Single-electron transistors are written at the heterointerface of two oxides using an atomic force microscope tip, and the electrons in the device can be controlled by gating and the ferroelectric state of the heterostructure.

Guanglei Cheng
Pablo F. Siles
Jeremy Levy
Research17 Apr 2011
Nature Nanotechnology

Volume: 6, P: 343-347
A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

In vivo decorporation of U(VI) from bones is an unsolved challenge because of the formation of stable uranium phosphate complexes. Here, the authors develop a hydroxypyridonone-based ligand with strong uranium complexation and low cytotoxicity. They find this ligand effectively removes uranium from kidney and bones in mice, and is suitable for oral administration.

Xiaomei Wang
Xing Dai
Shuao Wang
ResearchOpen Access25 Jun 2019
Nature Communications

Volume: 10, P: 1-13
Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice

Ketamine is used for sedation and treatment of depression, but is also a drug of abuse. Here the authors show that ketamine modulates the endocannabinoid system in mice, and that this may contribute to its psychoactive effects.

Wei Xu
Hongchun Li
Xiaobo Cen
ResearchOpen Access24 Nov 2020
Nature Communications

Volume: 11, P: 1-19
Evolution of HER2-low expression from primary to paired metastatic gastric cancer lesions

Wen-Zhuo He
Yuan-Zhong Yang
Liang-Ping Xia
ResearchOpen Access15 Apr 2025
npj Precision Oncology

Volume: 9, P: 1-8
Listening to the verses: unveiling phonetic contrasts in Li Bai and Du Fu’s poetry

Yingying Meng
Yuwei Wan
Chunyu Kit
ResearchOpen Access13 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-17
Protein function prediction is improved by creating synthetic feature samples with generative adversarial networks

Training machine learning models to predict the function of proteins is limited by the availability of only a small amount of labelled training data. Training can be improved by employing generative adversarial networks to generate additional synthetic protein samples.

Cen Wan
David T. Jones
Research31 Aug 2020
Nature Machine Intelligence

Volume: 2, P: 540-550
Motivational system modulates brain responses during exploratory decision-making

Chia-Wei Li
Carol Yeh-Yun Lin
Danchi Tan
ResearchOpen Access04 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Plasma metabolomics of early parenteral nutrition followed with enteral nutrition in pancreatic surgery patients

Zhengyu Jiang
Cen Wen
Xiaoming Deng
ResearchOpen Access11 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia

A genomic analysis of 147 pediatric acute myeloid leukemia patients identifies extensive gene fusion events and mutations that expand our understanding of the genetic complexities of this cancer.

Chi-Keung Cheng
Yuk-Lin Yung
Margaret H. L. Ng
ResearchOpen Access31 Mar 2023
Communications Biology

Volume: 6, P: 1-16
Resting-state functional connectivity of salience network in schizophrenia and depression

Huan Huang
Cheng Chen
Huiling Wang
ResearchOpen Access01 Jul 2022
Scientific Reports

Volume: 12, P: 1-8
RNA-seq transcriptomic profiling of crassulacean acid metabolism pathway in Dendrobium catenatum

Long-Hai Zou
Xiao Wan
Yan Wang
ResearchOpen Access13 Nov 2018
Scientific Data

Volume: 5, P: 1-7
miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR

Lin Ji
Zhongjie Lin
Xiujun Cai
ResearchOpen Access20 Apr 2020
Cell Death & Disease

Volume: 11, P: 1-15
Chromosome genome assembly and annotation of the yellowbelly pufferfish with PacBio and Hi-C sequencing data

Yitao Zhou
Shijun Xiao
Zhen Huang
ResearchOpen Access08 Nov 2019
Scientific Data

Volume: 6, P: 1-8
Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Miao Zhao
Hui-Zhen Su
Wan-Jin Chen
ResearchOpen Access29 Nov 2022
Cell Discovery

Volume: 8, P: 1-17
Mining of novel secondary metabolite biosynthetic gene clusters from acid mine drainage

Ling Wang
Wan Liu
Guoqing Zhang
ResearchOpen Access09 Dec 2022
Scientific Data

Volume: 9, P: 1-12
mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1–GluA2 interaction in the nucleus accumbens

Hong-chun Li
Jia-mei Zhang
Xiao-bo Cen
Research14 Sept 2021
Acta Pharmacologica Sinica

Volume: 43, P: 295-306
A high-quality genome provides insights into the new taxonomic status and genomic characteristics of Cladopus chinensis (Podostemaceae)

Ting Xue
Xuehai Zheng
Youqiang Chen
ResearchOpen Access01 Apr 2020
Horticulture Research

Volume: 7, P: 1-16
Effects of behavioral patterns and network topology structures on Parrondo’s paradox

Ye Ye
Kang Hao Cheong
Neng-gang Xie
ResearchOpen Access15 Nov 2016
Scientific Reports

Volume: 6, P: 1-17
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1

Junjie Xu
Lin Ji
Xiujun Cai
ResearchOpen Access26 Dec 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-14

Search

Functional divergence and intron variability during evolution of angiosperm TERMINAL FLOWER1 (TFL1) genes

Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger

The Geminga supernova as a possible cause of the local interstellar bubble

Increased CO₂ fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast

Comparative effects of 10-Hz rTMS and iTBS on cortico-striatal connectivity in major depressive disorder: a sham-controlled study

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

Fusion of circulant singular spectrum analysis and multiscale local ternary patterns for effective spectral-spatial feature extraction and small sample hyperspectral image classification

A community effort to optimize sequence-based deep learning models of gene regulation

A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant

Recurrent chromosome reshuffling and the evolution of neo-sex chromosomes in parrots

Sketched oxide single-electron transistor

A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice

Evolution of HER2-low expression from primary to paired metastatic gastric cancer lesions

Listening to the verses: unveiling phonetic contrasts in Li Bai and Du Fu’s poetry

Protein function prediction is improved by creating synthetic feature samples with generative adversarial networks

Motivational system modulates brain responses during exploratory decision-making

Plasma metabolomics of early parenteral nutrition followed with enteral nutrition in pancreatic surgery patients

Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia

Resting-state functional connectivity of salience network in schizophrenia and depression

RNA-seq transcriptomic profiling of crassulacean acid metabolism pathway in Dendrobium catenatum

miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR

Chromosome genome assembly and annotation of the yellowbelly pufferfish with PacBio and Hi-C sequencing data

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Mining of novel secondary metabolite biosynthetic gene clusters from acid mine drainage

mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1–GluA2 interaction in the nucleus accumbens

A high-quality genome provides insights into the new taxonomic status and genomic characteristics of Cladopus chinensis (Podostemaceae)

Effects of behavioral patterns and network topology structures on Parrondo’s paradox

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1

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