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  • The physiological significance of low fatty acid synthesis in adipocytes remains unclear. Here, the authors show a protective role of this phenomenon by demonstrating that overproduction of fatty acids increases ROS production and results in adipocyte necroptosis and lipodystrophy.

    • Li Weng
    • Wen-Shuai Tang
    • Tong-Jin Zhao
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16