Nature Search

Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations

Maki Sakuma
Amy K. Wang
Wencke Walter
ResearchOpen Access09 Oct 2025
Leukemia

Volume: 39, P: 2872-2880
Correction: How T-lymphoblastic leukemia can be classified based on genetics using standard diagnostic techniques enhanced by whole genome sequencing

Janine Müller
Wencke Walter
Anna Stengel
Amendments and CorrectionsOpen Access16 Dec 2022
Leukemia

Volume: 37, P: 252
Solving Riddles Through Sequencing (SIRIUS): unlocking hematologic diagnoses by whole genome and transcriptome sequencing

Marietta Truger
Manja Meggendorfer
Torsten Haferlach
ResearchOpen Access19 Dec 2025
Leukemia

Volume: 40, P: 55-62
Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma

Tumor-intrinsic resistance mechanisms, including mutational events and immunoselection of mutant clones, were identified in 30 patients with multiple myeloma who experienced relapse after treatment with anti-BCMA CAR T cells and/or anti-BCMA bispecific T cell engagers (TCEs) or anti-GPRC5D TCE therapy.

Holly Lee
Sungwoo Ahn
Nizar J. Bahlis
ResearchOpen Access31 Aug 2023
Nature Medicine

Volume: 29, P: 2295-2306
The RNA N⁶-methyladenosine methylome coordinates long non-coding RNAs to mediate cancer drug resistance by activating PI3K signaling

Yanhong Tan
Changli Zhou
Shujun Liu
ResearchOpen Access07 Nov 2025
Cell Death & Disease

Volume: 16, P: 1-15
CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk

Genomic and transcriptomic analyses of chronic lymphoproliferative disorder of natural killer cells identifies somatic gain-of-function mutations in the chemokine gene CCL22 with cell-extrinsic effects. Mutations caused biased signaling downstream of the G-protein-coupled receptor for CCL22 and deregulated interactions with the hematopoietic microenvironment.

Constance Baer
Shunsuke Kimura
Charles G. Mullighan
Research05 May 2022
Nature Genetics

Volume: 54, P: 637-648
Sequential Notch activation regulates ventricular chamber development

De la Pompa and colleagues show that Dll4-mediated Notch signalling regulates trabeculation in the developing mouse endocardium, whereas Jag1/2-mediated Notch signalling in the myocardium drives compaction and ventricular maturation.

Gaetano D’Amato
Guillermo Luxán
José Luis de la Pompa
Research07 Dec 2015
Nature Cell Biology

Volume: 18, P: 7-20
Novel causative variants of VEXAS in UBA1 detected through whole genome transcriptome sequencing in a large cohort of hematological malignancies

Maki Sakuma
Piers Blombery
Wencke Walter
ResearchOpen Access23 Feb 2023
Leukemia

Volume: 37, P: 1080-1091
FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Anna Sperk
Antje Gabriel
Florian Bassermann
ResearchOpen Access16 Jul 2024
Leukemia

Volume: 38, P: 2027-2031
Genomic landscape of CCUS compared to MDS and its implications on risk prediction

Sandra Huber
Constance Baer
Claudia Haferlach
ResearchOpen Access10 May 2024
Leukemia

Volume: 38, P: 1634-1637
Parallel genomic analysis from paired bone marrow and peripheral blood samples of 200 cytopenic patients

Sandra Huber
Natalie Wossidlo
Claudia Haferlach
ResearchOpen Access28 May 2024
Leukemia

Volume: 38, P: 1626-1629
Ruxolitinib mediated paradoxical JAK2 hyperphosphorylation is due to the protection of activation loop tyrosines from phosphatases

Sivahari P. Gorantla
Lorenz Oelschläger
Nikolas von Bubnoff
ResearchOpen Access23 Apr 2025
Leukemia

Volume: 39, P: 1678-1691
Risk prediction in MDS: independent validation of the IPSS-M—ready for routine?

Constance Baer
Sandra Huber
Claudia Haferlach
ResearchOpen Access01 Feb 2023
Leukemia

Volume: 37, P: 938-941
How T-lymphoblastic leukemia can be classified based on genetics using standard diagnostic techniques enhanced by whole genome sequencing

Janine Müller
Wencke Walter
Anna Stengel
ResearchOpen Access05 Nov 2022
Leukemia

Volume: 37, P: 217-221
Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia

Sunisa Kongkiatkamon
Simona Pagliuca
Jaroslaw P. Maciejewski
Research29 Nov 2021
Leukemia

Volume: 36, P: 1185-1188
SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Inge van der Werf
Anna Wojtuszkiewicz
Jacqueline Cloos
ResearchOpen Access17 May 2021
Leukemia

Volume: 35, P: 2698-2702
Elemental analyses reveal distinct mineralization patterns in radular teeth of various molluscan taxa

Wencke Krings
Jan-Ole Brütt
Stanislav N. Gorb
ResearchOpen Access07 May 2022
Scientific Reports

Volume: 12, P: 1-16
Characterization of myeloproliferative neoplasms based on genetics only and prognostication of transformation to blast phase

Wencke Walter
Niroshan Nadarajah
Manja Meggendorfer
ResearchOpen Access28 Sept 2024
Leukemia

Volume: 38, P: 2644-2652
Correction: complex landscape of alternative splicing in myeloid neoplasms

Courtney E. Hershberger
Devlin C. Moyer
Richard A. Padgett
Amendments and Corrections13 Mar 2021
Leukemia

Volume: 35, P: 1226
Author Correction: SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Inge van der Werf
Anna Wojtuszkiewicz
Jacqueline Cloos
Amendments and CorrectionsOpen Access08 Jul 2021
Leukemia

Volume: 35, P: 2735
IDH1R132, IDH2R140 and IDH2R172 in AML: different genetic landscapes correlate with outcome and may influence targeted treatment strategies

Manja Meggendorfer
Luca Vincenzo Cappelli
Torsten Haferlach
Research30 Jan 2018
Leukemia

Volume: 32, P: 1249-1253
Feeding experiments on Vittina turrita (Mollusca, Gastropoda, Neritidae) reveal tooth contact areas and bent radular shape during foraging

Wencke Krings
Christine Hempel
Stanislav N. Gorb
ResearchOpen Access05 May 2021
Scientific Reports

Volume: 11, P: 1-18
Radular force performance of stylommatophoran gastropods (Mollusca) with distinct body masses

Wencke Krings
Charlotte Neumann
Stanislav N. Gorb
ResearchOpen Access18 May 2021
Scientific Reports

Volume: 11, P: 1-15
Rare germline alterations of myeloperoxidase predispose to myeloid neoplasms

Sunisa Kongkiatkamon
Laila Terkawi
Jaroslaw P. Maciejewski
Research27 Jun 2022
Leukemia

Volume: 36, P: 2086-2096
Aberrant somatic hypermutation of CCND1 generates non-coding drivers of mantle cell lymphomagenesis

Heiko Müller
Wencke Walter
Claudia Haferlach
ResearchOpen Access10 Feb 2022
Cancer Gene Therapy

Volume: 29, P: 484-493
Myeloid neoplasms with MYC-positive double minutes: towards recognition as a distinct entity

Isolde Summerer
Wencke Walter
Christian Pohlkamp
CorrespondenceOpen Access03 Mar 2025
Blood Cancer Journal

Volume: 15, P: 1-4
Complex landscape of alternative splicing in myeloid neoplasms

Courtney E. Hershberger
Devlin C. Moyer
Richard A. Padgett
Research04 Aug 2020
Leukemia

Volume: 35, P: 1108-1120
How artificial intelligence might disrupt diagnostics in hematology in the near future

Wencke Walter
Claudia Haferlach
Torsten Haferlach
ReviewsOpen Access08 Jun 2021
Oncogene

Volume: 40, P: 4271-4280

Search

Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations

Correction: How T-lymphoblastic leukemia can be classified based on genetics using standard diagnostic techniques enhanced by whole genome sequencing

Solving Riddles Through Sequencing (SIRIUS): unlocking hematologic diagnoses by whole genome and transcriptome sequencing

Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma

The RNA N⁶-methyladenosine methylome coordinates long non-coding RNAs to mediate cancer drug resistance by activating PI3K signaling

CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk

Sequential Notch activation regulates ventricular chamber development

Novel causative variants of VEXAS in UBA1 detected through whole genome transcriptome sequencing in a large cohort of hematological malignancies

FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells

Genomic landscape of CCUS compared to MDS and its implications on risk prediction

Parallel genomic analysis from paired bone marrow and peripheral blood samples of 200 cytopenic patients

Ruxolitinib mediated paradoxical JAK2 hyperphosphorylation is due to the protection of activation loop tyrosines from phosphatases

Risk prediction in MDS: independent validation of the IPSS-M—ready for routine?

How T-lymphoblastic leukemia can be classified based on genetics using standard diagnostic techniques enhanced by whole genome sequencing

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia

SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Elemental analyses reveal distinct mineralization patterns in radular teeth of various molluscan taxa

Characterization of myeloproliferative neoplasms based on genetics only and prognostication of transformation to blast phase

Correction: complex landscape of alternative splicing in myeloid neoplasms

Author Correction: SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

IDH1R132, IDH2R140 and IDH2R172 in AML: different genetic landscapes correlate with outcome and may influence targeted treatment strategies

Feeding experiments on Vittina turrita (Mollusca, Gastropoda, Neritidae) reveal tooth contact areas and bent radular shape during foraging

Radular force performance of stylommatophoran gastropods (Mollusca) with distinct body masses

Rare germline alterations of myeloperoxidase predispose to myeloid neoplasms

Aberrant somatic hypermutation of CCND1 generates non-coding drivers of mantle cell lymphomagenesis

Myeloid neoplasms with MYC-positive double minutes: towards recognition as a distinct entity

Complex landscape of alternative splicing in myeloid neoplasms

How artificial intelligence might disrupt diagnostics in hematology in the near future

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