Manthei et al. use negative stain electron microscopy, crosslinking, and hydrogen-deuterium exchange to better define the lecithin:cholesterol acyltransferase (LCAT)-high density lipoprotein (HDL) complex. They provide a rationale for why LCAT activity diminishes as HDL particles mature into a spherical shape.
- Kelly A. Manthei
- Dhabaleswar Patra
- John J. G. Tesmer
