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Advanced filters: Author: Whitney Pickens Clear advanced filters

  • The degree to which the conformation of the human metapneumovirus fusion (F) protein affects immunogenicity has been debated. Here, Hsieh et al. engineer prefusion-stabilized F variants with enhanced thermostability that elicit higher neutralizing antibody titers in mice than postfusion F.

    • Ching-Lin Hsieh
    • Scott A. Rush
    • Jason S. McLellan
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11