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Showing 1–29 of 29 results
Advanced filters: Author: Will R. Turner Clear advanced filters
  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477
  • Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode proteins potentially related to kidney development.

    • Cristian Pattaro
    • Alexander Teumer
    • Caroline S. Fox
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-19
  • Natural ecosystems and biodiversity must be made a bulwark against climate change, not a casualty of it, argue Will R. Turner, Michael Oppenheimer and David S. Wilcove.

    • Will R. Turner
    • Michael Oppenheimer
    • David S. Wilcove
    Comments & Opinion
    Nature
    Volume: 462, P: 278-279
  • Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

    • Dinesh Aggarwal
    • Andrew J. Page
    • Ewan M. Harrison
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13
  • Aardvark Weather, an end-to-end machine learning model, replaces the entire numerical weather prediction pipeline with a machine learning model, by producing accurate global and local forecasts without relying on numerical solvers, revolutionizing weather prediction with improved speed, accuracy and customization capabilities.

    • Anna Allen
    • Stratis Markou
    • Richard E. Turner
    ResearchOpen Access
    Nature
    Volume: 641, P: 1172-1179
  • Bringing together multiple models and databases on nature’s contributions to people, the authors map these contributions globally and determine the critical areas where their magnitude is the highest and where they provide the highest potential human benefit.

    • Rebecca Chaplin-Kramer
    • Rachel A. Neugarten
    • Reg A. Watson
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 7, P: 51-61
  • Avoiding catastrophic climate change requires that we avoid losing key natural carbon reserves. This study maps such irrecoverable carbon globally and finds a third of the remaining managed by Indigenous peoples and local communities and nearly a quarter in protected areas.

    • Monica L. Noon
    • Allie Goldstein
    • Will R. Turner
    ResearchOpen Access
    Nature Sustainability
    Volume: 5, P: 37-46
  • Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

    • Dami A. Collier
    • Anna De Marco
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 593, P: 136-141
  • Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

    • Steven A. Kemp
    • Dami A. Collier
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 592, P: 277-282
  • Neuronal plasticity is thought to be the source of several chronic neurological conditions, including tinnitus. Using a rodent model for noise-induced tinnitus, this study finds that reversing neural plasticity induced by the tinnitus can correct perceptual impairments caused by the ailment. Pairing tones with stimulation of the vagus nerve sharpened auditory neuron tuning and eliminated the physiological as well as behavioural correlates of the tinnitus. This proof of principle suggests that simply restoring normal neural activity to circuits that have been pathologically modified could provide a benefit in those ailments involving aberrant neural plasticity.

    • Navzer D. Engineer
    • Jonathan R. Riley
    • Michael P. Kilgard
    Research
    Nature
    Volume: 470, P: 101-104
  • A whole-genome alignment of 240 phylogenetically diverse species of eutherian mammal—including 131 previously uncharacterized species—from the Zoonomia Project provides data that support biological discovery, medical research and conservation.

    • Diane P. Genereux
    • Aitor Serres
    • Elinor K. Karlsson
    ResearchOpen Access
    Nature
    Volume: 587, P: 240-245
  • The SARS-CoV-2 Assessment of Viral Evolution (SAVE) programme provides a real-time risk assessment of SARS-CoV-2 variants with the potential to affect transmission, virulence and resistance to infection- and vaccine-induced immunity.

    • Marciela M. DeGrace
    • Elodie Ghedin
    • Mehul S. Suthar
    Reviews
    Nature
    Volume: 605, P: 640-652
  • In order to limit warming and the most severe consequences of climate change, net global carbon emissions must reach zero by 2050. Many ecosystems contain carbon that would be irrecoverable on this timescale if lost and must be protected to meet climate goals.

    • Allie Goldstein
    • Will R. Turner
    • David G. Hole
    Reviews
    Nature Climate Change
    Volume: 10, P: 287-295
  • Completely stopping fossil fuel use may not be enough to avoid dangerous climate change. Recent research on the mitigation potential of conservation, restoration, and improved land management demonstrates that natural solutions can reduce emissions and remove atmospheric CO2 while safeguarding food security and biodiversity.

    • Will R. Turner
    News & Views
    Nature Climate Change
    Volume: 8, P: 18-19
  • Recent data on the genetic and molecular basis of progeroid syndromes have shed light onto the nuclear metabolic defects that might accelerate ageing. What are the mechanistic features of progeroid syndromes? And how can these findings help us understand normal ageing?

    • Brian A. Kudlow
    • Brian K. Kennedy
    • Raymond J. Monnat Jr
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 8, P: 394-404
  • Extracellular vesicles (EVs) are released by most cell types, and they carry a cargo of protein and nucleic acid that reflects the cell of origin. Thompson and colleagues review current knowledge of the biology and function of EVs, including evidence for their involvement in neurodegenerative disease pathogenesis, and their potential as CNS-specific biomarkers.

    • Alexander G. Thompson
    • Elizabeth Gray
    • Martin R. Turner
    Reviews
    Nature Reviews Neurology
    Volume: 12, P: 346-357
  • Investors are increasingly asking businesses to disclose their climate risk and corresponding management strategies. A review of corporate adaptation strategies reveals limited consideration of broader risks to supply chains, customers and employees.

    • Allie Goldstein
    • Will R. Turner
    • David G. Hole
    Reviews
    Nature Climate Change
    Volume: 9, P: 18-25
  • Natasha Bertelsen et al. develop a computational model to categorize patients with autism spectrum disorder (ASD) into distinct subgroups, based on social-communicative or restricted repetitive behaviors. By integrating publicly available neuroimaging and genetic data, they report neural and molecular signatures in two of these subgroups, altogether highlighting subtle differences in neural circuitry and genomic networks that could underlie phenotypic differences among ASD patients.

    • Natasha Bertelsen
    • Isotta Landi
    • Michael V. Lombardo
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-13