Complete chiral symmetry breaking of an amino acid derivative is achieved by circularly polarized light irradiation of a solution of the racemate in contact with racemic crystals, followed by abrasive grinding. The chirality of the amino acid derivative in the resultant crystals is fully determined by the rotation sense of the irradiation.
- Wim L. Noorduin
- Arno A. C. Bode
- Elias Vlieg