Nature Search

Newly replicated DNA is associated with DNA topoisomerase II in cultured rat prostatic adenocarcinoma cells

William G. Nelson
Leroy F. Liu
Donald S. Coffey
Research10 Jul 1986
Nature

Volume: 322, P: 187-189
Human T-cell γ genes contain N segments and have marked junctional variability

Thomas Quertermous
William Strauss
J. G. Seidman
Research10 Jul 1986
Nature

Volume: 322, P: 184-187
Detection and sequence of mutations in the factor VIII gene of haemophiliacs

Jane Gitschier
William I. Wood
Richard M. Lawn
Research30 May 1985
Nature

Volume: 315, P: 427-430
Peptide-dependent recognition of H–2K^b by alloreactive cytotoxic T lymphocytes

William R. Heath
Melissa E. Hurd
Linda A. Sherman
Research26 Oct 1989
Nature

Volume: 341, P: 749-752
Interleukin-2 stimulates association of protein kinase C with plasma membrane

William L. Farrar
Wayne B. Anderson
Research01 May 1985
Nature

Volume: 315, P: 233-235
Darwinian evolution in the genealogy of haemoglobin

Morris Goodman
G. William Moore
Genji Matsuda
Research01 Feb 1975
Nature

Volume: 253, P: 603-608
A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

David B. Weiner
Jing Liu
Mark I. Greene
Research18 May 1989
Nature

Volume: 339, P: 230-231
Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

TGF-β family cytokines control essential cell fate decisions via receptor regulated SMAD (R-SMAD) transcription factors. Here the authors identify an inner nuclear membrane phosphatase complex that dephosphorylates R-SMADs to inactivate TGF-β signaling.

Zhe Ji
Wing-Yan Skyla Siu
Pedro Carvalho
ResearchOpen Access11 Apr 2025
Nature Communications

Volume: 16, P: 1-14
The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a^18H mice

William L. Perry
Carolyn M. Hustad
Neal G. Copeland
Research01 Feb 1998
Nature Genetics

Volume: 18, P: 143-146
Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen

Pauline Johnson
Alan F. Williams
Research04 Sept 1986
Nature

Volume: 323, P: 74-76
Author Correction: ARF4-mediated intracellular transport as a broad-spectrum antiviral target

Ming-Yuan Li
Kao Deng
Cheng-Feng Qin
Amendments and Corrections23 Jun 2025
Nature Microbiology

Volume: 10, P: 2353
Non-invasive screening in hereditary cancer: a randomized controlled trial to test cell-free DNA-based early detection in the CHARM consortium

Kirsten M. Farncombe
Julia A. Sobotka
Raymond H. Kim
ReviewsOpen Access29 Jan 2026
European Journal of Human Genetics

P: 1-11
ARF4-mediated intracellular transport as a broad-spectrum antiviral target

ARF4 GTPase activity is needed for vesicular trafficking for multiple RNA viruses. Blocking ARF4 using specific peptides redirects viral progeny to lysosomal degradation and decreases influenza and Zika virus infection in mice.

Ming-Yuan Li
Kao Deng
Cheng-Feng Qin
Research19 Feb 2025
Nature Microbiology

Volume: 10, P: 710-723
Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Human memory and marginal zone B cells share some features including CD27 expression and somatic hypermutation, but their lineage relationship is still unclear. Here the authors use mass cytometry and sequential clustering methods to show that, despite their shared features, memory and marginal zone B cells represent distinct lineage choices.

Yuan Zhao
Mohamed Uduman
Jo Spencer
ResearchOpen Access21 Sept 2018
Nature Communications

Volume: 9, P: 1-15
A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

This Registered Report presents evidence from 87 countries and regions showing that brief emotion-regulation interventions consistently reduced negative emotions and increased positive emotions during the COVID-19 pandemic.

Ke Wang
Amit Goldenberg
Hannah Moshontz
Research02 Aug 2021
Nature Human Behaviour

Volume: 5, P: 1089-1110
1360 THE APGAR SCORE REVISITED: DEVELOPMENTAL PATTERNS IN “OPTIMAL” NEWBORNS

Elizabeth A Catlin
Marshall W J Carpenter
William Oh
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 337
1359 BILIRUBIN (BR) FLUX AND DISTRIBUTION IN THE BRAIN

William J Cashore
Philip Blazar
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 337
Elastin: mutational spectrum in supravalvular aortic stenosis

Kay Metcalfe
Agnes K Rucka
Mayada Tassabehji
Research20 Dec 2000
European Journal of Human Genetics

Volume: 8, P: 955-963
Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo

Martin Donnelley
Kaye S. Morgan
David W. Parsons
ResearchOpen Access14 Jan 2014
Scientific Reports

Volume: 4, P: 1-7
A cell for all reasons

The soil amoeba Dictyostelium discoideum is among the most versatile of model organisms. At a meeting last month, scientists who use Dictyostelium to study a wide variety of biological processes came together to discuss the latest results.

William F. Loomis
Robert H. Insall
News & Views30 Sept 1999
Nature

Volume: 401, P: 440-441
Mutations of the BRAF gene in human cancer

Helen Davies
Graham R. Bignell
P. Andrew Futreal
Research09 Jun 2002
Nature

Volume: 417, P: 949-954
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles

Virus triggered lipophagy is important for flaviviral assembly and coordinated by Aup1 and the ubiquitin conjugating enzyme E2. Here, Lan et al further characterise the interplay between these proteins and how they function to modulate selective autophagy and viral replication.

Yun Lan
Sophie Wilhelmina van Leur
Sumana Sanyal
ResearchOpen Access10 May 2023
Nature Communications

Volume: 14, P: 1-15
Long term relationship between farming damselfish, predators, competitors and benthic habitat on coral reefs of Moorea Island

William E. Feeney
Frédéric Bertucci
David Lecchini
ResearchOpen Access15 Jul 2021
Scientific Reports

Volume: 11, P: 1-8
Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns

Here, Wong et al investigate the cell-free DNA landscape of individuals with Li-Fraumeni syndrome (LFS), a cancer predisposition, and find altered composition compared to non-LFS individuals which can be used to detect and track cancer development.

Derek Wong
Maha Tageldein
Trevor J. Pugh
ResearchOpen Access27 Aug 2024
Nature Communications

Volume: 15, P: 1-16
NSD1 mutations generate a genome-wide DNA methylation signature

Sotos syndrome is an growth syndrome characterized by advanced growth in childhood, characteristic facial appearance and intellectual disability. Here the authors identify a genome-wide DNA methylation signature that accurately diagnoses Sotos Syndrome and distinguishes it from similar conditions.

S. Choufani
C. Cytrynbaum
R. Weksberg
ResearchOpen Access22 Dec 2015
Nature Communications

Volume: 6, P: 1-7
DNA evidence of bowhead whale exploitation by Greenlandic Paleo-Inuit 4,000 years ago

Our current understanding of the demographic history of Greenland relies on preserved fossils. Here, the authors sequence ancient DNA from four midden deposits and find a prominent role for caribou, walrus and whale species in Paleo-Inuit cultures not evident from the fossil record.

Frederik Valeur Seersholm
Mikkel Winther Pedersen
Anders Johannes Hansen
ResearchOpen Access08 Nov 2016
Nature Communications

Volume: 7, P: 1-9
Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection

The antiviral factor ISG15 can be conjugated to other proteins through ISGylation. Sanyal and colleagues find that viruses can modulate ISGylation, which in turn alters macrophage responses and can result in exaggerated inflammation in COVID-19.

Deeksha Munnur
Qiwen Teo
Sumana Sanyal
Research18 Oct 2021
Nature Immunology

Volume: 22, P: 1416-1427
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome

William Dobyns, Daniela Pilz and colleagues show that de novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome, a developmental disorder characterized by distinct craniofacial features, ocular colobomata and defects in neuronal migration.

Jean-Baptiste Rivière
Bregje W M van Bon
William B Dobyns
Research26 Feb 2012
Nature Genetics

Volume: 44, P: 440-444
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles

Egress of flaviviruses and involved host pathways are not well understood. Here, the authors show that Lyn is a critical host kinase for Dengue and Zika virus egress resulting in infectious virus progenies within autophagosome-derived vesicles, which might help the virus to evade antibody responses.

Ming Yuan Li
Trupti Shivaprasad Naik
Sumana Sanyal
ResearchOpen Access15 Oct 2020
Nature Communications

Volume: 11, P: 1-16
Facilitating a culture of responsible and effective sharing of cancer genome data

Lillian L Siu
Mark Lawler
Emile E Voest
Reviews05 May 2016
Nature Medicine

Volume: 22, P: 464-471
Effects of Valproic Acid on β-adrenergic Receptors, G-proteins, and Adenylyl Cyclase in Rat C6 Glioma Cells

Guang Chen
Husseini K Manji
William Z Potter
Research01 Sept 1996
Neuropsychopharmacology

Volume: 15, P: 271-280
Fetal Erythropoietin Levels in Growth-Restricted and Appropriately Grown Neonates With and Without Abnormal Fetal Heart Rate Tracings: A Comparison With Cord Blood Gases and Apgar Scores

Allahyar Jazayeri
John C M Tsibris
William N Spellacy
Research09 Dec 1999
Journal of Perinatology

Volume: 19, P: 255-259
Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Ke Wang
Amit Goldenberg
Hannah Moshontz
Amendments and Corrections24 Aug 2022
Nature Human Behaviour

Volume: 6, P: 1318-1319
G-Protein Level Quantification in Platelets and Leukocytes from Patients with Panic Disorder

Murray B Stein
Guang Chen
Husseini K Manji
Research01 Aug 1996
Neuropsychopharmacology

Volume: 15, P: 180-186
Human Proteinpedia enables sharing of human protein data

Suresh Mathivanan
Mukhtar Ahmed
Akhilesh Pandey
Correspondence01 Feb 2008
Nature Biotechnology

Volume: 26, P: 164-167
MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

MicroRNAs are frequently expressed in clusters, which often prevent the attribution of an individual microRNA to a specific function. Single overexpression of miR17, a microRNA belonging to a six-microRNA cluster, shows it controls heart, spleen and liver development by targeting fibronectin.

Sze Wan Shan
Daniel Y. Lee
Burton B. Yang
Research26 Jul 2009
Nature Cell Biology

Volume: 11, P: 1031-1038
Transitioning metal–organic frameworks from the laboratory to market through applied research

Metal–organic frameworks are a class of materials that have attracted researchers for over 25 years and have been proposed for many applications. This Perspective discusses critical topics in applied research for commercialization, and highlights challenges associated with product development.

Ashley M. Wright
Matthew T. Kapelewski
William Morris
Reviews08 Aug 2024
Nature Materials

Volume: 24, P: 178-187
The Psychological Science Accelerator’s COVID-19 rapid-response dataset

Erin M. Buchanan
Savannah C. Lewis
Maximilian A. Primbs
ResearchOpen Access11 Feb 2023
Scientific Data

Volume: 10, P: 1-15
Breeding for soil-borne pathogen resistance impacts active rhizosphere microbiome of common bean

Lucas William Mendes
Rodrigo Mendes
Siu Mui Tsai
Research17 Jul 2018
The ISME Journal

Volume: 12, P: 3038-3042
Paternal smoking and maternal protective behaviors at home on infant’s saliva cotinine levels

Man-ping Wang
Yi-nam Suen
Sophia Siu-chee Chan
Research13 Dec 2017
Pediatric Research

Volume: 83, P: 936-942
Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication

Wenyan Nong, Zhe Qu, Yiqian Li, Tom Barton-Owen, Annette Wong and colleagues provide genomes and small RNA transcriptomes for the mangrove horseshoe crab and the tri-spine horseshoe crab. They show that horseshoe crabs have undergone three rounds of whole genome duplication and shed light on how gene families and microRNAS evolved following this genome duplication event.

Wenyan Nong
Zhe Qu
Jerome H. L. Hui
ResearchOpen Access19 Jan 2021
Communications Biology

Volume: 4, P: 1-11
MITI minimum information guidelines for highly multiplexed tissue images

The imminent release of tissue atlases combining multichannel microscopy with single-cell sequencing and other omics data from normal and diseased specimens creates an urgent need for data and metadata standards to guide data deposition, curation and release. We describe a Minimum Information about Highly Multiplexed Tissue Imaging (MITI) standard that applies best practices developed for genomics and for other microscopy data to highly multiplexed tissue images and traditional histology.

Denis Schapiro
Clarence Yapp
Peter K. Sorger
Comments & Opinion11 Mar 2022
Nature Methods

Volume: 19, P: 262-267
“I just wanted more”: Hereditary cancer syndromes patients’ perspectives on the utility of circulating tumour DNA testing for cancer screening

Ella Adi-Wauran
Marc Clausen
Yvonne Bombard
Research11 Oct 2023
European Journal of Human Genetics

Volume: 32, P: 176-181
A community-sourced glossary of open scholarship terms

Open scholarship has transformed research, and introduced a host of new terms in the lexicon of researchers. The ‘Framework for Open and Reproducible Research Teaching’ (FORRT) community presents a crowdsourced glossary of open scholarship terms to facilitate education and effective communication between experts and newcomers.

Sam Parsons
Flávio Azevedo
Balazs Aczel
Comments & Opinion21 Feb 2022
Nature Human Behaviour

Volume: 6, P: 312-318
A fast and fully-automated deep-learning approach for accurate hemorrhage segmentation and volume quantification in non-contrast whole-head CT

Ali Arab
Betty Chinda
Xiaowei Song
ResearchOpen Access09 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

The COBRA toolbox provides quality-controlled reconstruction, modeling, topological analysis, and network visualization, as well as network integration of chemoinformatic, metabolomic, transcriptomic, proteomic, and thermochemical data.

Laurent Heirendt
Sylvain Arreckx
Ronan M. T. Fleming
Protocols20 Feb 2019
Nature Protocols

Volume: 14, P: 639-702
Baraitser–Winter cerebrofrontofacial syndrome: delineation of the spectrum in 42 cases

Alain Verloes
Nataliya Di Donato
Daniela T Pilz
Research23 Jul 2014
European Journal of Human Genetics

Volume: 23, P: 292-301
Novel structural co-expression analysis linking the NPM1-associated ribosomal biogenesis network to chronic myelogenous leukemia

Lawrence WC Chan
Xihong Lin
Benjamin YM Yung
ResearchOpen Access24 Jul 2015
Scientific Reports

Volume: 5, P: 1-13
Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles

Shan Zhao
Chun Man Li
Sidney Yu
ResearchOpen Access27 Feb 2017
Scientific Reports

Volume: 7, P: 1-12
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Debra Van Egeren
Khushi Kohli
Zenta Walther
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-6

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