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Showing 1–50 of 60 results

Advanced filters: Author: William T. McBride Clear advanced filters

New method for mapping genes in human chromosomes

Stephen J. Goss
Henry Harris
Research26 Jun 1975
Nature

Volume: 255, P: 680-684
Characterization of antitumor immunization to a defined melanoma antigen using genetically engineered murine dendritic cells

Antoni Ribas
Lisa H Butterfield
James S Economou
Research06 Dec 1999
Cancer Gene Therapy

Volume: 6, P: 523-536
Predicting aqueous aluminium concentrations in natural waters

Christopher S. Cronan
William J. Walker
Paul R. Bloom
Research13 Nov 1986
Nature

Volume: 324, P: 140-143
Immunoglobulin Administration and Ribavirin Therapy: Efficacy in Respiratory Syncytial Virus Infection of the Cotton Rat

William C Gruber
Samuel Z Wilson
Philip R Wyde
Research01 Mar 1987
Pediatric Research

Volume: 21, P: 270-274
Language gap

IAIN DAVIDSON
WILLIAM NOBLE
Research30 Jan 1992
Nature

Volume: 355, P: 403-404
Central Opioid Receptors Differentially Regulate the Nalmefene-Induced Suppression of Ethanol- and Saccharin-Reinforced Behaviors in Alcohol-Preferring (P) Rats

Harry L June
Rancia Cummings
Dynesha Mason
Research05 Nov 2003
Neuropsychopharmacology

Volume: 29, P: 285-299
Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor

Taro Shirakawa
Airong Li
Julian M. Hopkin
Research01 Jun 1994
Nature Genetics

Volume: 7, P: 125-130
Dispersion of the ras family of transforming genes to four different chromosomes in man

Stephen J. O'Brien
William G. Nash
Esther H. Chang
Research28 Apr 1983
Nature

Volume: 302, P: 839-842
The role of the ubiquitin/proteasome system in cellular responses to radiation

William H McBride
Keisuke S Iwamoto
Frank Pajonk
Reviews28 Aug 2003
Oncogene

Volume: 22, P: 5755-5773
Combining radiation therapy with interleukin-3 gene immunotherapy

Chi-Shiun Chiang
Ji-Hong Hong
Graeme J Dougherty
Research13 Sept 2000
Cancer Gene Therapy

Volume: 7, P: 1172-1178
Antitumoral Activity of the Fern Cibotium schiedei

WILLIAM A. CREASEY
Research28 Jun 1969
Nature

Volume: 222, P: 1281-1282
Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Bruce T. Lamb
Sangram S. Sisodia
John D. Gearhart
Research01 Sept 1993
Nature Genetics

Volume: 5, P: 22-30
An early Cambrian rift to post-rift transition in the Cordillera of western North America

Gerard C. Bond
Nicholas Christie-Blick
William J. Devlin
Research01 Jun 1985
Nature

Volume: 315, P: 742-746
Sex Chromosome Abnormalities

RICHARD M. GOODMAN
WILLIAM S. SMITH
CLAUDE J. MIGEON
Research02 Dec 1967
Nature

Volume: 216, P: 942-943
Policy advice: Use experts wisely

Policymakers are ignoring evidence on how advisers make judgements and predictions, warn William J. Sutherland and Mark A. Burgman.

William J. Sutherland
Mark Burgman
Comments & Opinion14 Oct 2015
Nature

Volume: 526, P: 317-318
The β-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus

Tom Glaser
William H. Lewis
D. E. Housman
Research26 Jun 1986
Nature

Volume: 321, P: 882-887
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Longitudinal genomic and transcriptomic profiling of 1,143 patients with multiple myeloma by the Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile study yields an improved copy number and gene expression subtype scheme, most notably a high-risk proliferative subtype associated with complete loss of RB1 or MAX.

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
ResearchOpen Access19 Aug 2024
Nature Genetics

Volume: 56, P: 1878-1889
Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

The effects of antibiotics on the gut microbiota can lead to enhanced colonization of Clostridioides difficile (C. difficile) and toxin-mediated pathogenesis. Here, using defined toxin-mutant strains and a murine model, the authors provide insights into how toxin-induced inflammation alters C. difficile metabolism, host tissue gene expression and gut microbiota, together influencing a beneficial niche for infection.

Joshua R. Fletcher
Colleen M. Pike
Casey M. Theriot
ResearchOpen Access19 Jan 2021
Nature Communications

Volume: 12, P: 1-14
Improved reference genome of Aedes aegypti informs arbovirus vector control

An improved, fully re-annotated Aedes aegypti genome assembly (AaegL5) provides insights into the sex-determining M locus, chemosensory systems that help mosquitoes to hunt humans and loci involved in insecticide resistance and will help to generate intervention strategies to fight this deadly disease vector.

Benjamin J. Matthews
Olga Dudchenko
Leslie B. Vosshall
ResearchOpen Access14 Nov 2018
Nature

Volume: 563, P: 501-507
Neutralization of SARS-CoV-2 variants by convalescent and BNT162b2 vaccinated serum

Here, the authors show that neutralization of human sera from both BNT162b2 vaccine recipients and from convalescent COVID-19 patients is less efficient against SARS- CoV-2 variants B.1.1.7 and B.1.351 and negatively associated with patient age.

Timothy A. Bates
Hans C. Leier
Fikadu G. Tafesse
ResearchOpen Access26 Aug 2021
Nature Communications

Volume: 12, P: 1-7
Radiotherapy for genes that cause cancer

William H. Mcbride
Graeme J. Dougherty
Advertorial01 Nov 1995
Nature Medicine

Volume: 1, P: 1215-1217
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody

Robert M Sharkey
Thomas M Cardillo
David M Goldenberg
Research30 Oct 2005
Nature Medicine

Volume: 11, P: 1250-1255
Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors

BRAF inhibitors often show skin-hyperproliferative side effects in melanoma patients. Here, the authors demonstrate that BRAF inhibitors can be used to enhance skin wound healing through the MAPK- ERK pathway activation that positively regulates the proliferation of keratinocytes.

Helena Escuin-Ordinas
Shuoran Li
Antoni Ribas
ResearchOpen Access01 Aug 2016
Nature Communications

Volume: 7, P: 1-10
PTPσ inhibitors promote hematopoietic stem cell regeneration

Protein tyrosine phosphatase sigma (PTPσ) deficient haematopoietic stem cells (HSCs) demonstrate increased engraftment following transplantation. Here the authors identify a small molecule inhibitor of PTPσ that promotes murine and human haematopoietic stem cell regeneration via induction of the RAC pathway and BCL-X_L.

Yurun Zhang
Martina Roos
John P. Chute
ResearchOpen Access14 Aug 2019
Nature Communications

Volume: 10, P: 1-15
Fish mouths as engineering structures for vortical cross-step filtration

Suspension-feeding fish, such as goldfish and whale sharks, retain prey without clogging their oral filter. Using a cross-step filtration model based on fish morphology, Sanderson et al. show how vortices generated by this design could trap and transport particles even smaller than the filter pores.

S. Laurie Sanderson
Erin Roberts
Hannah Brooks
ResearchOpen Access29 Mar 2016
Nature Communications

Volume: 7, P: 1-9
Convergent and complementary selection shaped gains and losses of eusociality in sweat bees

Leveraging independent gains and losses of eusociality, the authors identify complementary signatures of selection in sweat bee genomes, including two proteins that bind and transport juvenile hormone.

Beryl M. Jones
Benjamin E. R. Rubin
Sarah D. Kocher
Research20 Mar 2023
Nature Ecology & Evolution

Volume: 7, P: 557-569
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Type 9 secretion system structures reveal a new protein transport mechanism

Cryo-electron microscopy structures of the protein-conducting translocon of the type 9 secretion system reveal its architecture and mechanism of translocation.

Frédéric Lauber
Justin C. Deme
Ben C. Berks
Research07 Nov 2018
Nature

Volume: 564, P: 77-82
Stratifying risk of acute kidney injury in pre and post cardiac surgery patients using a novel biomarker-based algorithm and clinical risk score

William T. McBride
Mary Jo Kurth
Mark W. Ruddock
ResearchOpen Access18 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
Soft epitaxy of nanocrystal superlattices

Epitaxial crystal growth is widely used in electronics for the rational design of efficient devices. Here, Rupich et al. find a universal law for island size scaling, which outlines similarities and differences between self-assembly of nanocrystals and atomic epitaxial growth.

Sara M. Rupich
Fernando C. Castro
Dmitri V. Talapin
Research01 Dec 2014
Nature Communications

Volume: 5, P: 1-10
The Reinforcing Properties of Alcohol are Mediated by GABA_A1 Receptors in the Ventral Pallidum

Harry L June
Katrina L Foster
Phil Skolnick
Research20 May 2003
Neuropsychopharmacology

Volume: 28, P: 2124-2137
Opportunities and challenges of radiotherapy for treating cancer

Although dramatic changes in the delivery of radiation therapy have occurred, the impact of radiobiology on the clinic has been far less substantial. New advances are uncovering some of the mechanistic processes that underlie the differences between the tumour and host tissue characteristics. The authors of this Review focus on how these processes might be targeted to improve the outcome of radiotherapy for patients.

Dörthe Schaue
William H. McBride
Reviews30 Jun 2015
Nature Reviews Clinical Oncology

Volume: 12, P: 527-540
Structure and mechanism of the proton-driven motor that powers type 9 secretion and gliding motility

Using cryo-electron microscopy, the authors describe the structure and function of a molecular motor powering both the Bacteroidetes type 9 protein secretion system and the associated gliding motility apparatus.

Rory Hennell James
Justin C. Deme
Susan M. Lea
Research11 Jan 2021
Nature Microbiology

Volume: 6, P: 221-233
The Effects of Clozapine on Symptom Reduction, Neurocognitive Function, and Clinical Management in Treatment-Refractory State Hospital Schizophrenic Inpatients

Anne L Hoff
William O Faustman
John G Csernansky
Research01 Oct 1996
Neuropsychopharmacology

Volume: 15, P: 361-369
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

The Rat Genome Sequencing and Mapping Consortium reports a combined sequence-based and genetic mapping analysis of 160 phenotypes in an outbred rat heterogeneous stock. They identify 31 genes involved in 27 different phenotypes.

Amelie Baud
Roel Hermsen
Jonathan Flint
Research26 May 2013
Nature Genetics

Volume: 45, P: 767-775
Subverting misconceptions about radiation therapy

Silvia C Formenti
Sandra Demaria
William H McBride
Correspondence22 Mar 2016
Nature Immunology

Volume: 17, P: 345
Acute kidney injury risk in orthopaedic trauma patients pre and post surgery using a biomarker algorithm and clinical risk score

Mary Jo Kurth
William T. McBride
Mark W. Ruddock
ResearchOpen Access17 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
Prediction of fat mass from anthropometry at ages 7 to 9 years in Samoans: a cross-sectional study in the Ola Tuputupua’e cohort

Courtney C. Choy
William Johnson
Nicola L. Hawley
Research09 Jan 2023
European Journal of Clinical Nutrition

Volume: 77, P: 495-502
STING directly interacts with PAR to promote apoptosis upon acute ionizing radiation-mediated DNA damage

Yirong Sun
Saba R. Aliyari
Genhong Cheng
ResearchOpen Access12 Feb 2025
Cell Death & Differentiation

Volume: 32, P: 1167-1179
Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity

Nigel George Ternan
Nicola Diana Moore
Geoff McMullan
ResearchOpen Access12 Nov 2018
Scientific Reports

Volume: 8, P: 1-16
Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas

Sixtina Gil Diez de Medina
Dominique Chopin
François Radvanyi
Research23 Jan 1997
Oncogene

Volume: 14, P: 323-330
Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation

Delivering MR1 ligand in the context of an MR1 monomer demonstrates transfer of this ligand onto cellular MR1. The stabilization of an inherently unstable ligand in the monomer has implications for antigen delivery and possibly vaccine design.

Corinna A. Kulicke
Gwendolyn M. Swarbrick
Melanie J. Harriff
ResearchOpen Access24 Feb 2024
Communications Biology

Volume: 7, P: 1-13
Long-term developmental progression in infants and young children taking sapropterin for phenylketonuria: a two-year analysis of safety and efficacy

Nicola Longo
Komudi Siriwardena
Suyash Prasad
ResearchOpen Access18 Sept 2014
Genetics in Medicine

Volume: 17, P: 365-373
Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells

Jennifer A Wargo
Lana Y Schumacher
Antoni Ribas
Research18 Mar 2005
Cancer Gene Therapy

Volume: 12, P: 516-527
Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase

Weixiong Zhong
Larry W Oberley
Daret K St Clair
Research30 Jan 1997
Oncogene

Volume: 14, P: 481-490
Dopamine and Benzodiazepine-Dependent Mechanisms Regulate the EtOH-Enhanced Locomotor Stimulation in the GABA_A α1 Subunit Null Mutant Mice

Harry L June Sr
Katrina L Foster
Gregg E Homanics
Research17 May 2006
Neuropsychopharmacology

Volume: 32, P: 137-152
Alcohol Stimulates the Release of Dopamine in the Ventral Pallidum but not in the Globus Pallidus: A Dual-Probe Microdialysis Study

Roberto I Melendez
Zachary A Rodd-Henricks
James M Murphy
Research08 Oct 2002
Neuropsychopharmacology

Volume: 28, P: 939-946
Quantification of lifetime accumulated ELF-EMF exposure from household appliances in the context of a retrospective epidemiological case–control study

Thomas Behrens
Claudia Terschüren
Wolfgang Hoffmann
Research11 Mar 2004
Journal of Exposure Science & Environmental Epidemiology

Volume: 14, P: 144-153
Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development

Alison R. Weiss
William A. Liguore
Jodi L. McBride
ResearchOpen Access24 Apr 2020
Scientific Reports

Volume: 10, P: 1-14
Prions and their lethal journey to the brain

For some prion diseases, accumulation of the disease agent in lymphoid tissues is required for efficient delivery of the agent to the central nervous system. Here, Mabbott and MacPherson discuss the cellular components and mechanisms involved before, during and after this accumulation.

Neil A. Mabbott
G. Gordon MacPherson
Reviews06 Feb 2006
Nature Reviews Microbiology

Volume: 4, P: 201-211

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