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Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1

Authors explore the biological mechanisms underlying a missing digit joint in Brachydactyly type A1. They showed that excess Indian Hedgehog proteins suppress the apoptosis level needed for the progression of digit joint development in a mouse model.

Adrian On Wah Leung
Andrew Chung Hin Poon
Danny Chan
ResearchOpen Access12 Mar 2024
Nature Communications

Volume: 15, P: 1-19
Preventive Pharmacotherapy for Cardiovascular Disease: A Modelling Study Considering Health Gain, Costs, and Cost-Effectiveness when Stratifying by Absolute Risk

Nhung Nghiem
Josh Knight
Nick Wilson
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-10

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Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1

Preventive Pharmacotherapy for Cardiovascular Disease: A Modelling Study Considering Health Gain, Costs, and Cost-Effectiveness when Stratifying by Absolute Risk

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