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Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism

ErbB2 is a receptor tyrosine kinase that localizes to the plasma membrane. Dinget al. now show that ErbB2 also localizes to mitochondria, where it regulates mitochondrial respiratory function and resistance to cancer chemotherapy.

Yan Ding
Zixing Liu
Ming Tan
Research11 Dec 2012
Nature Communications

Volume: 3, P: 1-12
MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans

Anusha Angajala
Hughley Raymond
Clayton Yates
ResearchOpen Access22 Dec 2022
Scientific Reports

Volume: 12, P: 1-14

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Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism

MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans

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