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Showing 1–4 of 4 results
Advanced filters: Author: Winthrop F. Gillis Clear advanced filters
  • Photometric recordings and optogenetic manipulation show that dopamine fluctuations in the dorsolateral striatum in mice modulate the use, sequencing and vigour of behavioural modules during spontaneous behaviour.

    • Jeffrey E. Markowitz
    • Winthrop F. Gillis
    • Sandeep Robert Datta
    ResearchOpen Access
    Nature
    Volume: 614, P: 108-117
  • Keypoint-MoSeq is an unsupervised behavior segmentation algorithm that extracts behavioral modules from keypoint tracking data acquired with diverse algorithms, as demonstrated in mice, rats and fruit flies. The extracted modules faithfully reflect human-annotated behaviors even though they are obtained in an unsupervised fashion.

    • Caleb Weinreb
    • Jonah E. Pearl
    • Sandeep Robert Datta
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 1329-1339
  • Motion Sequencing uses three-dimensional machine vision and unsupervised machine learning on depth videos to decompose spontaneous mouse behavior into a series of elemental modules called ‘syllables’, revealing how often syllables are used and how they transition over time.

    • Sherry Lin
    • Winthrop F. Gillis
    • Sandeep Robert Datta
    Protocols
    Nature Protocols
    Volume: 19, P: 3242-3291
  • By analyzing hundreds of mice treated with a library of neuro- and psychoactive drugs, Wiltschko et al. show that Motion Sequencing can effectively discriminate and categorize drug effects and link molecular targets to behavioral syllables.

    • Alexander B. Wiltschko
    • Tatsuya Tsukahara
    • Sandeep Robert Datta
    Research
    Nature Neuroscience
    Volume: 23, P: 1433-1443