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Showing 1–5 of 5 results
Advanced filters: Author: Woody Sherman Clear advanced filters
  • Using a large cosmological sample of FRBs, Connor et al. have located many of the Universe’s unseen baryons, finding that most reside in the diffuse intergalactic medium, not galaxies—confirming the strong astrophysical feedback seen in simulations.

    • Liam Connor
    • Vikram Ravi
    • Ralf M. Konietzka
    Research
    Nature Astronomy
    Volume: 9, P: 1226-1239
  • The formation of ternary degrader-protein complexes is a key step in the targeted degradation of proteins of interest. Here, the authors explore the structure and dynamics of such complexes applying high-performance computer simulations augmented with experimental data.

    • Tom Dixon
    • Derek MacPherson
    • Jesus A. Izaguirre
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-24
  • Analysis of the stellar population properties of 30 host galaxies of fast radio bursts (FRBs) suggests an abundance of FRBs in massive star-forming galaxies, and implies that the formation of FRB sources—magnetars—is linked to core-collapse supernovae of stellar merger remnants.

    • Kritti Sharma
    • Vikram Ravi
    • Yuhan Yao
    Research
    Nature
    Volume: 635, P: 61-66
  • A structurally diverse set of epigenetic reader proteins can recognize methylated lysine residues on histones. Here the authors show that recognition of trimethyllysine occurs through a combination of favourable cation–πinteractions and the release of water molecules occupying the aromatic cages of reader proteins.

    • Jos J.A.G. Kamps
    • Jiaxin Huang
    • Jasmin Mecinović
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-12
  • Lysine trimethylation is a key post-translational modification, which some epigenetic reader proteins detect through binding to aromatic cages involving cation-π interactions. Here systematic modification of the aromatic cage reveals that weaker cation-π interactions do not correlate with weaker binding owing to a compensating release of bound water molecules.

    • Bas J. G. E. Pieters
    • Maud H. M. Wuts
    • Jasmin Mecinović
    ResearchOpen Access
    Communications Chemistry
    Volume: 3, P: 1-12