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  • Fibrinogen, a key blood clotting factor, is produced in the endoplasmic reticulum (ER) of hepatocytes. Here, authors uncover the vital role of ER- associated degradation in preventing fibrinogen aggregation and ensuring its proper biogenesis.

    • Zhenfeng Song
    • Pattaraporn Thepsuwan
    • Shengyi Sun
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17