Veins are the most commonly used conduits for surgical revascularization; however, they are associated with a high failure rate. In this Review, de Vries and colleagues discuss the pathophysiological mechanisms underlying the development of vein graft failure, and summarize the current and developing therapies used to prevent graft failure.
- Margreet R. de Vries
- Karin H. Simons
- Paul H. A. Quax