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Showing 1–3 of 3 results

Advanced filters: Author: Wyatt Beyers Clear advanced filters

Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7

Membrane trafficking is essential for organelle biogenesis. Here, the authors discover an alternative assembly of the Commander trafficking complex and show its role in melanosome biogenesis and in a subtype of albinism.

Rebeka Butkovič
Michael D. Healy
Peter J. Cullen
ResearchOpen Access02 Oct 2025
Nature Communications

Volume: 16, P: 1-21
Unmasking the FACES of membrane bilayers

Approaches to study lipid composition with leaflet-specific resolution in living cells have been lacking. A new method — fluorogen-activating coincidence encounter sensing (FACES) — combines biorthogonal metabolic labeling with organelle-targeted fluorogen-activating proteins to selectively visualize lipids on leaflets of interest in any organelle.

Wyatt Beyers
Chi-Lun Chang
News & Views11 Nov 2025
Nature Chemical Biology

Volume: 22, P: 11-12
Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2

Ponsawan Netcharoensirisuk
Carla Abrahamian
Christian Grimm
ResearchOpen Access19 Apr 2021
Scientific Reports

Volume: 11, P: 1-14