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Nature Cell Biology (1)

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Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest

Lin Li, Lei Li et al. perform single-cell multi-omics to study the transcriptome, the DNA methylome and chromatin accessibility in human arrested embryos and find that cytoskeletal defects cause embryonic arrest characterized by zygotic genome activation.

Teng Wang
Junhua Peng
Lin Li
Research18 Jan 2024
Nature Cell Biology

Volume: 26, P: 263-277

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Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest

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