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Showing 1–16 of 16 results
Advanced filters: Author: Xiaozhou Luo Clear advanced filters

  • Microbial production of cannabinoids promises a cheaper and more sustainable route to these important therapeutic molecules, but strain improvement and screening is challenging. Here, the authors develop a yeast-based Δ9-tetrahydrocannabinol (THC) biosensor for screening microbial mutant libraries.

    • William M. Shaw
    • Yunfeng Zhang
    • Tom Ellis
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • A propeptide strategy increases uptake of phosphotyrosine and a nonhydrolyzable analog to facilitate their incorporation into proteins by recombinant methods, aided by a specific aminoacyl-tRNA synthetase with a reconfigured active site.

    • Xiaozhou Luo
    • Guangsen Fu
    • Feng Wang
    Research
    Nature Chemical Biology
    Volume: 13, P: 845-849

  • Prediction of enzyme kinetic parameters is essential for designing and optimising enzymes for various biotechnological and industrial applications. Here, authors presented a prediction framework (UniKP), which improves the accuracy of predictions for three enzyme kinetic parameters.

    • Han Yu
    • Huaxiang Deng
    • Xiaozhou Luo
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Enzyme kinetic parameter prediction is a challenge in enzyme discovery and engineering. Here, the authors train a robust deep learning model CataPro to predict enzyme kinetic parameters and validate its practicality through wet-lab experiments.

    • Zechen Wang
    • Dongqi Xie
    • Liangzhen Zheng
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • The chemical synthesis of jasmonates is typically low yielding and can be laborious, whereas their extraction can be costly or environmentally hazardous. Now a de novo biosynthesis of jasmonic acid and its derivatives, methyl jasmonate and jasmonoyl isoleucine, is reported, using an engineered baker’s yeast.

    • Hongting Tang
    • Shumin Lin
    • Xiaozhou Luo
    Research
    Nature Synthesis
    Volume: 3, P: 224-235

  • Space charges or injected charges dominate the ferroelectric degradation, however, its physics insight remains unclear. Here, the authors reveal the nature of ferroelectric degradation in nanodevices and the role of the injected charges in polarization reversal.

    • Qianwei Huang
    • Zibin Chen
    • Xiaozhou Liao
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-7

  • Low-carbon chemicals generated from CO2 provide a possible path to improve the sustainability of microbial bioproduction of food and chemicals. Now, using a metabolic engineering approach, yeast is engineered to produce glucose, myo-inositol, glucosamine, sucrose and starch from C1–3 molecules.

    • Hongting Tang
    • Lianghuan Wu
    • Tao Yu
    Research
    Nature Catalysis
    Volume: 7, P: 21-34

  • Most attempts to co-cultivate the artificial microbial communities fail mostly due to the mismatched rates of consumption and production of nutrients among subpopulations. Here, the authors develop a microbial swarmbot mediated spatial segregation method to assemble stably coexisting consortia with both flexibility and precision.

    • Lin Wang
    • Xi Zhang
    • Zhuojun Dai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Dielectric capacitors are widely used in electronic systems but they possess inferior energy density in comparison with other electrochemical energy storage. Here, the authors construct a diffused phase boundary to simultaneously achieve high energy storage density and efficiency in AgNbO3antiferroelectrics.

    • Nengneng Luo
    • Kai Han
    • Yuezhou Wei
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • Combining alloy design with additive manufacturing process design creates α–β titanium–oxygen–iron alloys that are both strong and ductile, with the potential to revitalize off-grade sponge titanium and thereby reduce the carbon footprint of the titanium industry.

    • Tingting Song
    • Zibin Chen
    • Ma Qian
    ResearchOpen Access
    Nature
    Volume: 618, P: 63-68

  • In materials science, it is a well-accepted fact that metals are generally ductile, and ceramics are always brittle. Here, the authors observe high level of plasticity and excellent elasticity in perovskite oxide under compression and bending with diameter of 2.1 μm.

    • Ying Liu
    • Xiangyuan Cui
    • Julie M. Cairney
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9