Bacteria harness toxin-antitoxin systems to manipulate growth and evade stress. Using biochemistry, biophysics, and crystallography, the authors characterize a mechanism of antitoxin-induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis.
- Tom J. Arrowsmith
- Xibing Xu
- Tim R. Blower
