Exon–intron-fused RAB22A regulates metastasis of osteosarcoma. Liao et al. show that protein products resulting from chromosomal translocations involving RAB22A mediate release of GTP-bound RhoA, induce its activation and promote lung metastasis of osteosarcoma.
- Dan Liao
- Li Zhong
- Tiebang Kang
