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Polygenic risk score from steroid-sensitive nephrotic syndrome GWAS indicates overlapping genetic basis with steroid-resistant cases

Cong Wang
Guotao Yin
Shuzhen Sun
ResearchOpen Access03 Feb 2026
Scientific Reports

Volume: 16, P: 1-6
Construction of emissive ruthenium(II) metallacycle over 1000 nm wavelength for in vivo biomedical applications

Ruthenium (Ru(II)) compounds are of interest as platinum drug replacements but have suffered from suboptimal therapeutic efficiency. Here, the authors design a Ru(II) metallacycle with NIR excitation and emission wavelengths and demonstrate application for deep tumour imaging and chemo-photo therapy.

Yuling Xu
Chonglu Li
Yao Sun
ResearchOpen Access14 Apr 2022
Nature Communications

Volume: 13, P: 1-13
An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms

Chemoresistance is a main limitation for the treatment of pancreatic ductal adenocarcinoma (PDAC). Here, the authors show that an antibody drug conjugate-like compound targeting both EGFR and HER2 overcomes gemcitabine resistance in PDAC preclinical models by mechanisms involving the tumour suppressor SMAD4.

Hongjuan Yao
Wenping Song
Liang Li
ResearchOpen Access20 Sept 2022
Nature Communications

Volume: 13, P: 1-24
AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

Yuanyuan Guo
Cai Lin
Min Yao
ResearchOpen Access02 Nov 2016
Scientific Reports

Volume: 6, P: 1-16
Author Correction: AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

Yuanyuan Guo
Cai Lin
Min Yao
Amendments and CorrectionsOpen Access16 Jan 2024
Scientific Reports

Volume: 14, P: 1-5

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Polygenic risk score from steroid-sensitive nephrotic syndrome GWAS indicates overlapping genetic basis with steroid-resistant cases

Construction of emissive ruthenium(II) metallacycle over 1000 nm wavelength for in vivo biomedical applications

An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms

AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

Author Correction: AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

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