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Signal Transduction and Targeted Therapy (3)
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Showing 1–11 of 11 results

Advanced filters: Author: Xiuxuan Wang Clear advanced filters

Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2

Ke Wang
Peng Lin
Ping Zhu
ResearchOpen Access03 Feb 2026
Signal Transduction and Targeted Therapy

Volume: 11, P: 1-17
Publisher Correction: Acetylation profiling by Iseq-Kac reveals insights into HSC aging and lineage decision

Yanqiu Gong
Huiwen Zhan
Lunzhi Dai
Amendments and Corrections04 Jun 2025
Nature Chemical Biology

Volume: 21, P: 1828
Acetylation profiling by Iseq-Kac reveals insights into HSC aging and lineage decision

A method for acetylome profiling requiring a low quantity of hematopoietic stem cells (HSCs) was developed, revealing a significant reduction in H4K77ac in aged HSCs, associated with decreased lymphocyte differentiation potential.

Yanqiu Gong
Huiwen Zhan
Lunzhi Dai
Research26 May 2025
Nature Chemical Biology

Volume: 21, P: 1675-1687
Protein-level mutant p53 reporters identify druggable rare precancerous clones in noncancerous tissues

Wang and colleagues generate two protein-level mutant p53 reporters and use them to identify precancerous clones in normal tissues in vivo, characterized by increased amino acid metabolism and a transcriptomic signature that includes Ybx3.

Pengle Yao
Peng Xiao
Yuan Wang
Research03 Aug 2023
Nature Cancer

Volume: 4, P: 1176-1192
Author Correction to: TRIM29 negatively controls antiviral immune response through targeting STING for degradation

Qijie Li
Liangbin Lin
Hongbo Hu
Amendments and CorrectionsOpen Access31 May 2018
Cell Discovery

Volume: 4, P: 1
Immunological and metabolic characteristics of the Omicron variants infection

Jiejie Geng
Xu Yang
Liang Chen
ResearchOpen Access21 Jan 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-11
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

Jiejie Geng
Liang Chen
Zhi-Nan Chen
ResearchOpen Access25 Sept 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-13
Id2 epigenetically controls CD8⁺ T-cell exhaustion by disrupting the assembly of the Tcf3-LSD1 complex

Yiming Li
Mingwei Han
Liang Chen
ResearchOpen Access29 Jan 2024
Cellular & Molecular Immunology

Volume: 21, P: 292-308
TRIM29 negatively controls antiviral immune response through targeting STING for degradation

Qijie Li
Liangbin Lin
Hongbo Hu
ResearchOpen Access20 Mar 2018
Cell Discovery

Volume: 4, P: 1-13
UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination

Meilin Ma
Changhui Zhang
Xianghui Fu
Research22 Oct 2022
Oncogene

Volume: 41, P: 5199-5213
Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway

He Huang
Zhouqing Luo
Yingming Zhao
Research01 Dec 2017
Cell Research

Volume: 28, P: 111-125