Nature Search

Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11

Sihan Miao
Xiaoyi Dai
Qi Zheng
ResearchOpen Access10 Dec 2025
Cell Death Discovery

Volume: 12, P: 1-18
Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant

A combination of adenovirus-vectored and subunit protein intranasal vaccine enhances immune response against SARS-CoV-2 variants in animal models and humans.

Weiqi Hong
Ping Cheng
Xiawei Wei
ResearchOpen Access22 Sept 2025
Nature Biomedical Engineering

P: 1-19
Genome sequencing of ‘Fuji’ apple clonal varieties reveals genetic mechanism of the spur-type morphology

Spur-type of growth is preferred for apple production. Here, the authors employ the trio-based phasing approach to assemble a fully phased Fuji genome and reveal the association of a 167-bp deletion in the promoter region of the MdTCP11 gene with the spur-type varieties.

Yudong Cai
Xiuhua Gao
Dong Zhang
ResearchOpen Access21 Nov 2024
Nature Communications

Volume: 15, P: 1-14
The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing

The mechanism driving inflammatory-to-proliferative state transition during wound healing remains unclear. Here, the authors discover that SNHG26 interacts with ILF2, redirecting it from inflammatory genomic loci to the LAMB3 locus, thereby promoting wound healing.

Dongqing Li
Zhuang Liu
Ning Xu Landén
ResearchOpen Access05 Oct 2024
Nature Communications

Volume: 15, P: 1-19
Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.

Puping Liang
Xiaowei Xie
Zhou Songyang
ResearchOpen Access08 Jan 2019
Nature Communications

Volume: 10, P: 1-9
Integrative network pharmacology and multi-omics reveal anisodamine hydrobromide’s multi-target mechanisms in sepsis

Ying Chen
Danlei Weng
Shubin Guo
ResearchOpen Access31 Jul 2025
Scientific Reports

Volume: 15, P: 1-24
Inverse relationship between species competitiveness and intraspecific trait variability may enable species coexistence in experimental seedling communities

Intraspecific trait variation could influence competitive interactions among species. Here, the authors show that higher intraspecific variation in seedling traits and performance may enable competitively inferior plant species to coexist with competitively superior species.

Jing Yang
Xiya Wang
Guochun Shen
ResearchOpen Access03 Apr 2024
Nature Communications

Volume: 15, P: 1-12
Boosting hydrogen evolution on MoS₂ via co-confining selenium in surface and cobalt in inner layer

The lack of efficient, inexpensive catalysts hinders large-scale application of hydrogen evolution reaction (HER). Here, the authors report a MoS₂ nanofoam catalyst with co-confined Se in the surface and Co in the inner layer, exhibiting high large-current-density HER activity and durability.

Zhilong Zheng
Liang Yu
Dehui Deng
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-10
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity

Shizan Xu
Peiqin Niu
Chuanyong Guo
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-12
From digitalization to green transformation: empirical evidence from RCEP’s industrial sectors

Lu Wan
Xiya Wan
Guohua Huang
ResearchOpen Access03 Feb 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-15
Intranasal delivery of a subunit protein vaccine provides protective immunity against JN.1 and XBB-lineage variants

Hong Lei
Weiqi Hong
Xiawei Wei
ResearchOpen Access20 Nov 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-13
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

Cheng-Long Hu
Bing-Yi Chen
Lan Wang
ResearchOpen Access27 Oct 2022
Cell Research

Volume: 32, P: 1105-1123
Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2

Fulian Lyu
Huanle Gong
Depei Wu
Research23 Nov 2024
Leukemia

Volume: 39, P: 473-481
Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy

Zhengyu Jiang
Lulong Bo
Xiaoming Deng
ResearchOpen Access28 Aug 2018
Cell Death & Disease

Volume: 9, P: 1-16
Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1

Yang Chen
Yaran Wu
Yingbin Yang
ResearchOpen Access23 Jul 2020
Cell Death & Disease

Volume: 11, P: 1-13
PDCL2 is essential for spermiogenesis and male fertility in mice

Minyan Li
Yuxi Chen
Xiya Zhang
ResearchOpen Access17 Oct 2022
Cell Death Discovery

Volume: 8, P: 1-9
Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility

Yuxi Chen
Puping Liang
Junjiu Huang
ResearchOpen Access22 Aug 2017
Cell Discovery

Volume: 3, P: 1-18
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways

Liwei Wu
Qinghui Zhang
Chuanyong Guo
ResearchOpen Access24 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway

Tong Liu
QingHui Zhang
Chuanyong Guo
ResearchOpen Access21 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death

Sainan Li
Jingjing Li
Chuanyong Guo
ResearchOpen Access19 Sept 2017
British Journal of Cancer

Volume: 117, P: 1518-1528

Search

Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11

Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant

Genome sequencing of ‘Fuji’ apple clonal varieties reveals genetic mechanism of the spur-type morphology

The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Integrative network pharmacology and multi-omics reveal anisodamine hydrobromide’s multi-target mechanisms in sepsis

Inverse relationship between species competitiveness and intraspecific trait variability may enable species coexistence in experimental seedling communities

Boosting hydrogen evolution on MoS₂ via co-confining selenium in surface and cobalt in inner layer

The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity

From digitalization to green transformation: empirical evidence from RCEP’s industrial sectors

Intranasal delivery of a subunit protein vaccine provides protective immunity against JN.1 and XBB-lineage variants

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2

Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy

Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1

PDCL2 is essential for spermiogenesis and male fertility in mice

Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways

The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway

Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death

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