Asymmetric dioxygenation of alkenes is an attractive concept to synthesize enantioenriched diols, but the performance in the case of terminal alkenes is low with current methods. Now, this has been addressed by an asymmetric oxypalladation process that provides access to enantioenriched 1,2-diols, enabled by the chiral 6-modified pyridinyl oxazoline ligand.
- Bing Tian
- Pinhong Chen
- Guosheng Liu
