Nature Search

Inhibition of glycosphingolipid synthesis overcomes the steric hindrance of CD30 N-glycans to augment CD30-targeted immunotherapeutic efficacy

Yuting Pan
Yixin Chang
Weidong Han
Research27 Apr 2026
Cellular & Molecular Immunology

P: 1-13
Analysis of the mediating effect of social status perception on professional identity and work engagement of blood purification nurses

Jia Wanning
Dong Wan
He Wenwen
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-8
JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

Previous work suggested that histone demethylase JMJD3 is detrimental to somatic cell reprogramming. Here, the authors show that while JMJD3 has a context-independent detrimental effect on early stages of reprogramming, during late stages it activates epithelial and pluripotency genes together with Klf4.

Yinghua Huang
Hui Zhang
Baoming Qin
ResearchOpen Access08 Oct 2020
Nature Communications

Volume: 11, P: 1-16
An ACC–VTA–ACC positive-feedback loop mediates the persistence of neuropathic pain and emotional consequences

This study identifies a positive-feedback loop between the ACC and the VTA that mediates the mutual exacerbation between hyperalgesia and comorbid anxiodepressive-like behaviors and, thereby, the chronicity of neuropathic pain.

Qian Song
Anqi Wei
Changhe Wang
Research03 Jan 2024
Nature Neuroscience

Volume: 27, P: 272-285
Synaptotagmin-11 deficiency mediates schizophrenia-like behaviors in mice via dopamine over-transmission

Schizophrenia is a severe psychiatric disorder and the pathogenesis remains unclear. Here, the authors show a potential role for synaptotagmin-11 in schizophrenia-related behavior through dopamine over-transmission.

Yang Chen
Yuhao Gu
Changhe Wang
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-23
Valence-skipping and quasi-two-dimensionality of superconductivity in a van der Waals insulator

Fluctuation of the cation valence state plays a crucial role in emergent quantum phenomena in correlated electron systems. Here, the authors demonstrate a valence-fluctuation-driven insulator-to-superconductor transition in the van der Waals insulator GeP as a function of hydrostatic pressure.

Caorong Zhang
Junwei Huang
Hongtao Yuan
ResearchOpen Access14 Nov 2022
Nature Communications

Volume: 13, P: 1-9
Sarcopenia is independently associated with diabetic foot disease

Qingfeng Cheng
Jinbo Hu
Qifu Li
ResearchOpen Access21 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse

Jie Li
Wei Xia
Ningsheng Shao
ResearchOpen Access17 May 2016
Scientific Reports

Volume: 6, P: 1-10
Pausing pluripotency via RNA methylation

Embryonic diapause in development and paused pluripotency in embryonic stem cells result in a state of hypotranscription through mechanisms that remain unclear. A new study dissects the role of METTL3-deposited global m⁶A RNA methylation in mediating this transcriptional dormancy.

Xueting Xu
Baoming Qin
News & Views07 Sept 2023
Nature Cell Biology

Volume: 25, P: 1241-1242
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination

Liver metastases reduce clinical and preclinical immune-checkpoint inhibitor efficacy through hepatic siphoning of circulating activated CD8⁺ T cells, but therapeutic benefit can be improved by combining immunotherapy with liver-directed radiotherapy.

Jiali Yu
Michael D. Green
Weiping Zou
Research04 Jan 2021
Nature Medicine

Volume: 27, P: 152-164
The molecular basis of μ-opioid receptor signaling plasticity

Huibing Zhang
Xueting Wang
Yan Zhang
ResearchOpen Access07 Nov 2025
Cell Research

Volume: 35, P: 1021-1036
Observation of charge–parity symmetry breaking in baryon decays

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

R. Aaij
A. S. W. Abdelmotteleb
G. Zunica
ResearchOpen Access16 Jul 2025
Nature

Volume: 643, P: 1223-1228
CD52 signaling via macrophage Siglec-G represents a therapeutic target for cancer immunotherapy

Xueting Qin
Yixin Chang
Jing Nie
ResearchOpen Access24 Jan 2026
npj Breast Cancer

Volume: 12, P: 1-11
Correlation between surrogate endpoints and overall survival in unresectable hepatocellular carcinoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

Litao Huang
Deying Kang
Xueting Liu
ResearchOpen Access21 Feb 2024
Scientific Reports

Volume: 14, P: 1-12
Direct ring-strain loading for visible-light accelerated bioorthogonal ligation via diarylsydnone-dibenzo[b,f ][1,4,5]thiadiazepine photo-click reactions

Strained alkenes are valuable reagents for rapid and selective labeling of biomolecules but may undergo side-reactions. Here direct excitation of an azobenzene generates a strained nitrogen-nitrogen double bond in situ which reacts with a photochemically-generated nitrile imine, allowing the labeling of live cells with spatiotemporal control.

Jingshuo Gao
Qin Xiong
Zhipeng Yu
ResearchOpen Access04 Mar 2020
Communications Chemistry

Volume: 3, P: 1-10
An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells

Jie Li
Jie Dong
Ningsheng Shao
ResearchOpen Access02 Aug 2017
Scientific Reports

Volume: 7, P: 1-12

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