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Showing 1–15 of 15 results

Advanced filters: Author: Xuming Deng Clear advanced filters

Stevioside curbs Streptococcus pneumoniae infection via inhibiting capsule biosynthesis

Stevioside is an inhibitor of Streptococcus pneumoniae capsule biosynthesis by disrupting pyruvate metabolism and redox balance, it reduces capsular polysaccharide formation, enhances immune clearance, and protects from pneumococcal infection.

Sanwei Gu
Jian Zhang
Tingting Wang
ResearchOpen Access09 Jan 2026
Communications Biology

Volume: 9, P: 1-15
Deep learning framework based on ITOC optimization for coal spontaneous combustion temperature prediction: a coupled CNN-BiGRU-CBAM model

Xuming Shao
Wenhao Liu
Jiahe Guang
ResearchOpen Access23 Jul 2025
Scientific Reports

Volume: 15, P: 1-20
MDM2-P53-V-ATPases axis driven by dehydroevodiamine to fight intracellular bacterial infection

Lysosomal activation via the MDM2-P53-V-ATPase axis unveils a potent host-directed strategy for eradicating intracellular pathogens and potentiating conventional antimicrobial therapy.

Heng Wang
Xinyue He
Jianfeng Wang
ResearchOpen Access13 Dec 2025
Communications Biology

Volume: 9, P: 1-15
Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death

The bacterial pathogen Legionella pneumophila delivers hundreds of effector proteins to promote infection. Here, Ge et al show that effector LegK3 suppresses host apoptosis via direct phosphorylation of caspases.

Jinli Ge
Ying Wang
Jiazhang Qiu
ResearchOpen Access30 Sept 2024
Nature Communications

Volume: 15, P: 1-14
A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes

A high-quality genome assembly of Weining rye sheds new light on gene duplications and their effects on starch biosynthesis genes, gene expression features underlying early heading trait and putative domestication-associated chromosomal regions.

Guangwei Li
Lijian Wang
Daowen Wang
ResearchOpen Access18 Mar 2021
Nature Genetics

Volume: 53, P: 574-584
Magnolol restores the activity of meropenem against NDM-1-producing Escherichia coli by inhibiting the activity of metallo-beta-lactamase

Shui Liu
Yonglin Zhou
Xuming Deng
ResearchOpen Access20 Feb 2018
Cell Death Discovery

Volume: 4, P: 1-8
Insights into structure and activity of natural compound inhibitors of pneumolysin

Hongen Li
Xiaoran Zhao
Liping Peng
ResearchOpen Access06 Feb 2017
Scientific Reports

Volume: 7, P: 1-8
Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling

Jianfeng Wang
Xuan Zhou
Xiaodi Niu
ResearchOpen Access09 Mar 2015
Scientific Reports

Volume: 5, P: 1-7
Probing the Na metal solid electrolyte interphase via cryo-transmission electron microscopy

The solid electrolyte interphase (SEI) strongly affects the cycling behaviour of rechargeable alkali metal cells. Here, the authors investigate via cryo-electron microscopy the SEI formed on a Na metal electrode using fluoroethylene carbonate-containing electrolyte.

Bing Han
Yucheng Zou
Meng Gu
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-8
Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins

Zhenxu Shi
Zhimin Guo
Jiazhang Qiu
ResearchOpen Access06 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

Jianfeng Wang
Xuan Zhou
Xiaodi Niu
ResearchOpen Access27 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy

Chengyan Wang
Xuming Tang
Hongkui Deng
Research23 Aug 2011
Cell Research

Volume: 22, P: 194-207
Commercialized artemisinin derivatives combined with colistin protect against critical Gram-negative bacterial infection

The anti-malaria drugs artemisinin derivatives produce a synergistic antibacterial effect with colistin against Gram-negative bacteria by simultaneously inhibiting MCR-1 function and hindering flagella assembly and energy metabolism.

Yonglin Zhou
Baichen Liu
Jianfeng Wang
ResearchOpen Access08 Sept 2022
Communications Biology

Volume: 5, P: 1-15
Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A

Hongming Lv
Huahong Yang
Xinxin Ci
ResearchOpen Access05 Apr 2019
Cell Death & Disease

Volume: 10, P: 1-15
β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection

Hongen Li
Xiaoran Zhao
Xuming Deng
ResearchOpen Access03 Dec 2015
Scientific Reports

Volume: 5, P: 1-9

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Stevioside curbs Streptococcus pneumoniae infection via inhibiting capsule biosynthesis

Deep learning framework based on ITOC optimization for coal spontaneous combustion temperature prediction: a coupled CNN-BiGRU-CBAM model

MDM2-P53-V-ATPases axis driven by dehydroevodiamine to fight intracellular bacterial infection

Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death

A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes

Magnolol restores the activity of meropenem against NDM-1-producing Escherichia coli by inhibiting the activity of metallo-beta-lactamase

Insights into structure and activity of natural compound inhibitors of pneumolysin

Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling

Probing the Na metal solid electrolyte interphase via cryo-transmission electron microscopy

Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy

Commercialized artemisinin derivatives combined with colistin protect against critical Gram-negative bacterial infection

Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A

β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection

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