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Showing 1–3 of 3 results

Advanced filters: Author: Xunian Zhou Clear advanced filters

Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

Kalluri and colleagues use mammary carcinoma models to study the causes of metastatic organotropism and find an organ-specific role for angiopoietin 2 in driving lung metastasis through the suppression of the tight junction protein Claudin 5.

Xunian Zhou
Valerie S. LeBleu
Raghu Kalluri
Research17 Sept 2024
Nature Cancer

Volume: 5, P: 1371-1389
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker

Using an unbiased and quantitative proteomic approach, Kugeratski et al. identified the core constituents of exosomes and found that syntenin-1 was the most abundant component, making it a putative universal biomarker.

Fernanda G. Kugeratski
Kelly Hodge
Raghu Kalluri
Research09 Jun 2021
Nature Cell Biology

Volume: 23, P: 631-641
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species

Mingyue Li
Li-Hua Song
Clara Bik-San Lau
ResearchOpen Access09 Feb 2017
Scientific Reports

Volume: 7, P: 1-13