Double-hydrophilic diblock copolymers, PSB4n-b-PGalMm, comprising a polymethacrylate bearing galactose units and a polymethacrylate bearing sulfobetaine groups, exhibited unique miscibility inversions between dilute and concentrated regimes and between block copolymers and blends. These inversions were attributed to concentration-dependent χeff and solution-specific driving forces. Aqueous systems with periodically arranged zwitterionic and pyranose units represent a novel class of molecular assemblies resembling cell membranes, featuring arrays of zwitterions and glycocalyxes, and hold promise for the interfacial design of biomaterials.
- Yuji Higaki
- Miyuka Tateyama
- Yoshiko Miura
