The range of Hedgehog (Hh) signalling in the Drosophila imaginal disc is limited by Hh/receptor degradation at the anterior/posterior (A/P) compartment boundary. Here, the authors show that degradation is mediated by co-receptor proteins Ihog/Boi, whose cell adhesion functions also contribute to A/P cell segregation.
- Elaine Y. C. Hsia
- Ya Zhang
- Xiaoyan Zheng
