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Immunogenicity and safety of a recombinant gE-Fc fusion protein subunit vaccine for herpes zoster in adults ≥50 years of age: a randomised, active-controlled, non-inferiority trial

In this clinical trial, the authors demonstrate that recombinant gE-Fc Fusion Protein Vaccine LZ901 for herpes zoster induces superior cellular immunogenicity and exhibits a better safety profile than HZ/su in adults ≥50 years, supporting its potential as vaccine candidate.

Peng-Fei Jin
Ya-Ru Quan
Jing-Xin Li
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Single nucleus RNA-seq reveals the process from onset to chronic kidney disease in IgA nephropathy

Jun-Peng You
Gen-Yang Cheng
Zhan-Zheng Zhao
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Dihydro-stilbene gigantol relieves CCl₄-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver

Ya-ru Xue
Sheng Yao
Guo-yu Pan
Research13 May 2020
Acta Pharmacologica Sinica

Volume: 41, P: 1433-1445
Clinical utility of cerebrospinal fluid Alzheimer’s disease biomarkers in the diagnostic workup of complex patients with cognitive impairment

Ming-Yu Wang
Ke-Liang Chen
Jin-Tai Yu
ResearchOpen Access07 Apr 2025
Translational Psychiatry

Volume: 15, P: 1-10
Head-to-head comparison of 6 plasma biomarkers in early multiple system atrophy

Yu Guo
Xue-Ning Shen
Jin-Tai Yu
ResearchOpen Access15 Mar 2023
npj Parkinson's Disease

Volume: 9, P: 1-9
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes

Ya-li Wu
Ya-ru Xue
Xing-xing Diao
Research25 May 2021
Acta Pharmacologica Sinica

Volume: 43, P: 747-756
Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity

Yang Xie
Xu Zhou
Cheng-gang Huang
Research23 May 2018
Acta Pharmacologica Sinica

Volume: 39, P: 1923-1934

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Immunogenicity and safety of a recombinant gE-Fc fusion protein subunit vaccine for herpes zoster in adults ≥50 years of age: a randomised, active-controlled, non-inferiority trial

Single nucleus RNA-seq reveals the process from onset to chronic kidney disease in IgA nephropathy

Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver

Clinical utility of cerebrospinal fluid Alzheimer’s disease biomarkers in the diagnostic workup of complex patients with cognitive impairment

Head-to-head comparison of 6 plasma biomarkers in early multiple system atrophy

Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes

Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity

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Dihydro-stilbene gigantol relieves CCl₄-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver