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Fast-charging black phosphorus electrodes are limited by slow multiphase redox reactions. Here, authors engineer P–N bonds in the phosphorus bulk to accelerate lithium insertion and boost performance. Pouch cells can hit 80% charge in 10 min, delivering 282 Wh/kg and lasting over 3,400 cycles.

Fe-based polyanionic cathodes are promising for large-scale Na-ion batteries but are limited by incomplete Na utilization. Now, research shows that tuning the local Na coordination via V substitution in phosphate-based cathode allows additional Na sites to participate, enabling near-complete Na utilization, enhancing energy density and cycling stability.

Global Burden of Disease analysis found that in 2023, suboptimal diet was estimated to be responsible for 4 million deaths and 97 million morbidity burdens from ischemic heart disease.

Peatland degradation raised soil pH, depleted lignin- and lipid-rich carbon, increased hydrolytic enzymes and carbon dioxide emissions, and reduced soil multifunctionality via consistent shifts in microbial β diversity, based on a field study from Northeast China coupled with global meta-analysis.

IP6 is a critical host cofactor for HIV-1 assembly and infectivity. In this study, the authors uncover the structural basis by which HIV-1 adapts to a deficiency in IP6 packaging through a G225R mutation at the C-terminus of the capsid protein.

This study uncovers a unique broad neutralization mechanism against rotavirus, where antibody 7H13 destabilizes the partial structure of the viral VP4 spike by acting on a critical residue switch located at the interface of multiple VP4 subunits.

Targeted deletion of integrin-associated protein CD47 enhances long-term engraftment of human CD34⁺ cells in immunodeficient pigs lacking IL2RG and RAG2, enabling large-scale production of functional human immune cells.

Purifying C₂H₂ by removing trace CO₂ is needed but challenging due to their analogous physical properties. Herein, the authors report the pilot-scale production of a commercial resin adsorbent loaded with polyethyleneimine for the selective capture of CO₂ traces and exclusion of C₂H₂.

Particulate methane monooxygenase (pMMO) is the main enzyme used by methanotrophs. Here, the authors determined the native structure of pMMO by cryo-electron tomography, revealing lipid-stabilized features and a higher-order hexagonal array arrangement in intact cells.

Root-associated microbiota confers benefits to plant in responding to environmental stress. Here, the authors show that wild soybean secretes purines under salt stress, reshapes the microbiota and recruits Pseudomonas.

Alveolar bone resorption (ABR) is a key pathological manifestation in the development of apical periodontitis (AP) that contributes to the AP-associated tooth loss, and whose underlying mechanism is largely unknown. Here, the authors show a molecular mechanism on osteoclastogenesis-related ABR and provides a therapeutic target of AP via modulating the FTO/HK1/USP14/RANK axis.

Propylene and propane have similar physicochemical properties, and thus their separation is challenging. Now, as an alternative to energy-intensive cryogenic distillation methods, a molecular sieving adsorbent with high propylene adsorption capacity has been shown to sieve propylene from propylene/propane mixtures to yield high-purity propylene.

Migration centres in China show reduced levels of pollution discharge due to improved treatment efficiency in urban areas, according to analyses of spatial patterns of migration and subsequent environmental disturbances.

Currently, there are no treatments or vaccines against Epstein-Barr virus (EBV) infection. Here, Zhu et al. isolate gH/gL-specific antibodies from infected donors and identify 1D8, that substantially reduces infection levels in both, B- and epithelial cells, and reduces tumor burdens in EBV-challanged humanized mice due to interferance with the gH/gL-mediated membrane fusion and binding.

Postsynaptic NMDARs at spinal synapses are required for postsynaptic long-term potentiation and chronic pain. Here, the authors show that also presynaptic NMDARs in spinal nociceptor terminals modulate synaptic transmission in a nociceptive tone-dependent manner.

Preclinical characterization of the SARS-CoV-2 M^pro inhibitor RAY1216 shows improved in vivo pharmacokinetics compared with nirmatrelvir.

Two monoclonal antibodies isolated from a patient with COVID-19 are shown to interfere with SARS-CoV-2–receptor binding, and one displays potent action against this virus in vitro and in a rhesus macaque model.

Observations of optical flares from AT2022tsd (the ‘Tasmanian Devil’) show that they have durations on the timescale of minutes, occur over a period of months, are highly energetic, are probably nonthermal and have supernova luminosities.

4E-BP1 is a translational repressor critical in mTOR signaling, whereas Snail is a critical promoter of epithelial to mesenchymal transition. Here the authors show that Snail induces resistance to mTOR inhibitors by repressing 4E-BP1 expression and promoting cell cycle progression via upregulating cycD.

Carboxysomes are bacterial proteinaceous organelle encapsulating enzymes and pathways to enhance carbon fixation. Here, authors engineer and determine cryoEM structure of minimal α-carboxysome shells to uncover the principle of shell assembly and encapsulation by CsoS2.

How β-AR signaling coordinates epigenetic and transcriptional pathways is unknown. Here the authors show that cold-induced β-AR signaling negatively regulates MYPT1-PP1β phosphatase activity to orchestrate both pathways for beige adipogenesis.

Anti-HER2 resistance causes treatment failure in HER2-positive breast cancers. Here the authors identify FGFR4 as one of the vulnerabilities of anti-HER2 resistant breast cancer and show that FGRR4 inhibition enhances sensitivity to anti-HER2 treatment in these resistant cells by triggering ferroptosis.

Carboxysomes are bacterial microcompartments encapsulating Rubisco and carbonic anhydrase for carbon fixation. Here, authors determine the organization of Rubisco and its interaction with the linker protein CsoS2 within two distant α-carboxysomes.

This paper shows that desertification combating practices decline incomes of farmers and herders, and China needs to adapt its ecological programmes to address the impacts of climate change and create positive synergies to combat desertification.

Integrative exploration of the interaction between FXR - RXRα - DNA and SRC1 - NRID in this study illuminates allosteric communication and SRC1’s binding to FXR, offering insights into FXR’s function and its implications in disease.

Cryo-EM structures reveal that DSR2, a defense-associated sirtuin, recognizes SPR phage tail tube protein, activating its NADase activity and elucidating its role in bacterial anti-phage immunity and pathogen recognition.

The authors present a single-cell atlas of human lung samples comprising 45 cell types, which reveals dynamic transcriptional and phenotypic changes associated with development and aging.