Excessive production of reactive oxygen species (ROS) in cancer cells can induce immunogenic cell death (ICD) and promote anti-tumor immune responses. Here the authors report that intermetallics modified with glucose oxidase and soybean phospholipid as nano-inducers promote cancer cell pyroptosis and disulfidptosis, resulting in ICD and anti-tumor immunity in preclinical models.
- Yanlin Zhu
- Xinxin Wang
- Piaoping Yang
