Nature Search

Operando NMR electrochemical gating studies of ion dynamics in PEDOT:PSS

Understanding charge-compensating interactions and ionic dynamics in organic mixed conductors can be challenging. Operando NMR spectroscopy is now used to quantify cation and water movement during doping/dedoping in mixed conductor films.

Dongxun Lyu
Yanting Jin
Clare P. Grey
Research20 Apr 2023
Nature Materials

Volume: 22, P: 746-753
Androgens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome

Polycystic ovary syndrome is a common cause of female infertility linked to metabolic and hormonal imbalances. Here, the authors show that androgen driven SLC1A5 upregulation increases glutamine uptake, leading to abnormal follicular development in PCOS via histone deacetylation.

Yishu Wang
Jiaying Wu
Hefeng Huang
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-21
An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control

The ectoenzyme CD73 is often elevated in tumour environments and targeting this protein is a tumour therapeutic target. Here the authors characterise a therapeutic anti-CD73 antibody cocktail which is more effective than either antibody alone and suggest a molecular mechanism of how this antibody cocktail functions.

Jin-Gen Xu
Shi Chen
Li Wan
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-17
A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease

Array-based epigenome-wide association studies only test about 2% of the CpG sites in the genome. Here, the authors describe EWASplus, a supervised machine learning strategy that extends EWAS coverage to the entire genome, and use it to identify novel brain CpGs associated with Alzheimer’s disease.

Yanting Huang
Xiaobo Sun
Zhaohui S. Qin
ResearchOpen Access22 Jul 2021
Nature Communications

Volume: 12, P: 1-12
Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency

Pregestational hyperglycaemia in mothers increases the probability of glucose intolerance in the offspring, an effect controlled by TET3-dependent DNA demethylation of genes involved in insulin secretion.

Bin Chen
Ya-Rui Du
Hefeng Huang
Research18 May 2022
Nature

Volume: 605, P: 761-766
Expedient access to bora-butenolide bioisosteres by counteranion-mediated trans-hydroboration of alkynes

Boron-containing drug candidates have garnered increasing attention due to their pharmacological properties and application in boron neutron capture therapy. Here, the authors report a transition metal-free anti-addition of pinacolborane to alkynes, facilitated by the counteranion effect for the facile construction of bora-butenolide bioisosteres.

Yuan-Wen Liu
Yu Liu
Hongming Jin
ResearchOpen Access27 May 2025
Nature Communications

Volume: 16, P: 1-12
Prospective observational study on biomarkers of response in pancreatic ductal adenocarcinoma

Cohort-scale integration of clinical and proteomic data from tumor tissues in patients with pancreatic ductal adenocarcinoma led to the identification of a prognostic risk model for patient stratification as well as biomarkers of response to adjuvant chemotherapy, validated in independent external cohorts.

Lingxi Jiang
Jiejie Qin
Baiyong Shen
Research29 Jan 2024
Nature Medicine

Volume: 30, P: 749-761
Prediction of hematologic toxicity in luminal type breast cancer patients receiving neoadjuvant chemotherapy using CT L1 level skeletal muscle index

Min Chen
Pinxiu Wang
Wenzhen Yuan
ResearchOpen Access13 Apr 2024
Scientific Reports

Volume: 14, P: 1-8
Understanding the failure process of sulfide-based all-solid-state lithium batteries via operando nuclear magnetic resonance spectroscopy

All-solid-state lithium batteries performance is affected by the solid electrolyte interphase (SEI) and electrically disconnected (“dead”) Li metal. Here, via operando NMR measurements, the authors quantify the Li metal in the SEI and “dead” regions using various inorganic solid-state electrolytes.

Ziteng Liang
Yuxuan Xiang
Yong Yang
ResearchOpen Access17 Jan 2023
Nature Communications

Volume: 14, P: 1-15
A critical edge number revealed for phase stabilities of two-dimensional ball-stick polygons

The melting scenario of two-dimensional (2D) systems is sensitive to molecular details. Here the authors investigate the phase stabilities of 2D ball-stick polygons by molecular dynamics simulation and reveal a critical edge number of 4 emerging from the entropy-enthalpy balance.

Ruijian Zhu
Yanting Wang
ResearchOpen Access29 Jul 2024
Nature Communications

Volume: 15, P: 1-12
Visualizing the growth process of sodium microstructures in sodium batteries by in-situ ²³Na MRI and NMR spectroscopy

Magnetic resonance imaging and spectroscopy provide quantitative insights into the growth of sodium microstructures in batteries.

Yuxuan Xiang
Guorui Zheng
Yong Yang
Research27 Jul 2020
Nature Nanotechnology

Volume: 15, P: 883-890
The sonic hedgehog signaling inhibitor cyclopamine improves pulmonary arterial hypertension via regulating the bone morphogenetic protein receptor 2 pathway

Youpeng Jin
Fei Mao
Youfei Fan
ResearchOpen Access11 Apr 2025
Scientific Reports

Volume: 15, P: 1-14
A spatiotemporal transcriptomic atlas of mouse placentation

Yanting Wu
Kaizhen Su
Hefeng Huang
ResearchOpen Access22 Oct 2024
Cell Discovery

Volume: 10, P: 1-17
Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients

Weiqing Zhang
Jun Wu
Qian Zeng
ResearchOpen Access14 Sept 2021
Scientific Reports

Volume: 11, P: 1-11
The Bifidobacterium-dominated fecal microbiome in dairy calves shapes the characteristic growth phenotype of host

Yimin Zhuang
Shuai Liu
Zhijun Cao
ResearchOpen Access21 Jul 2024
npj Biofilms and Microbiomes

Volume: 10, P: 1-17
Prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study

Daya Zhang
Chen Chen
Feihu Bai
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-9
Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2

Yuying Han
Xiaoliang Gao
Jie Liang
ResearchOpen Access29 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-13
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X

Xiaoyi Zhang
Jin Han
Yanting Gu
Research21 Sept 2022
Cancer Gene Therapy

Volume: 30, P: 172-181
Very important pharmacogenetic variants landscape and potential clinical relevance in the Zhuang population from Yunnan province

Yujie Li
Yanting Chang
Tianbo Jin
ResearchOpen Access29 Mar 2024
Scientific Reports

Volume: 14, P: 1-16
A complex structure of arrestin-2 bound to a G protein-coupled receptor

Wanchao Yin
Zhihai Li
H. Eric Xu
Research27 Nov 2019
Cell Research

Volume: 29, P: 971-983
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins

Yanxia Jin
Jie Wang
Hui Sun
ResearchOpen Access23 Feb 2016
British Journal of Cancer

Volume: 114, P: 532-544
Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis

Ling Chen
Jie Ren
Yan Qiu
ResearchOpen Access27 Jan 2016
Scientific Reports

Volume: 6, P: 1-11
Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

Longhe Yang
Long Li
Yan Qiu
ResearchOpen Access27 Aug 2015
Scientific Reports

Volume: 5, P: 1-10
The United States COVID-19 Forecast Hub dataset

Estee Y. Cramer
Yuxin Huang
Nicholas G. Reich
ResearchOpen Access01 Aug 2022
Scientific Data

Volume: 9, P: 1-15
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes

Mingrui Xia
Jin Liu
Yong He
Research25 Mar 2022
Molecular Psychiatry

Volume: 27, P: 1384-1393

Search

Operando NMR electrochemical gating studies of ion dynamics in PEDOT:PSS

Androgens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome

An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control

A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease

Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency

Expedient access to bora-butenolide bioisosteres by counteranion-mediated trans-hydroboration of alkynes

Prospective observational study on biomarkers of response in pancreatic ductal adenocarcinoma

Prediction of hematologic toxicity in luminal type breast cancer patients receiving neoadjuvant chemotherapy using CT L1 level skeletal muscle index

Understanding the failure process of sulfide-based all-solid-state lithium batteries via operando nuclear magnetic resonance spectroscopy

A critical edge number revealed for phase stabilities of two-dimensional ball-stick polygons

Visualizing the growth process of sodium microstructures in sodium batteries by in-situ ²³Na MRI and NMR spectroscopy

The sonic hedgehog signaling inhibitor cyclopamine improves pulmonary arterial hypertension via regulating the bone morphogenetic protein receptor 2 pathway

A spatiotemporal transcriptomic atlas of mouse placentation

Changes in muscle ultrasound for the diagnosis of intensive care unit acquired weakness in critically ill patients

The Bifidobacterium-dominated fecal microbiome in dairy calves shapes the characteristic growth phenotype of host

Prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2

Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X

Very important pharmacogenetic variants landscape and potential clinical relevance in the Zhuang population from Yunnan province

A complex structure of arrestin-2 bound to a G protein-coupled receptor

Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins

Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

The United States COVID-19 Forecast Hub dataset

Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes

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