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Showing 1–8 of 8 results

Advanced filters: Author: Yaojie Lu Clear advanced filters

Structural insights into the activation mechanism of the human zinc-activated channel

ZAC is a Zn²⁺ and H⁺-activated cation channel. Here, the authors report the structures of human ZAC and identify an unusual C-tail that functions in auto-inhibition. This work provides insights into the gating and activation mechanisms of ZAC.

Xuhang Lu
Dongmei Li
Yuequan Shen
ResearchOpen Access07 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption

Fu, Mackowiak et al. show that cooperative action of the liver and the gut, rather than the liver alone, drives acetaldehyde clearance after alcohol consumption and modulates drinking behaviour.

Yaojie Fu
Bryan Mackowiak
Bin Gao
Research20 Jun 2024
Nature Metabolism

Volume: 6, P: 1380-1396
Molecular basis of Mg²⁺ permeation through the human mitochondrial Mrs2 channel

Mrs2 is a mitochondrial Mg2+ channel that is essential for metabolic function. Here, the authors present cryo-EM structures of human Mrs2 revealing symmetrical pentameric assembly and how Mrs2 permeates Mg²⁺.

Ming Li
Yang Li
Yuequan Shen
ResearchOpen Access05 Aug 2023
Nature Communications

Volume: 14, P: 1-11
Optical emission inventory of carbonaceous aerosol from the residential sector in China

Lu Zhang
Yaojie Li
Shu Tao
ResearchOpen Access21 Aug 2025
Scientific Data

Volume: 12, P: 1-6
Modelling and forecasting crude oil price volatility with climate policy uncertainty

Mengxi He
Yaojie Zhang
Danyan Wen
ResearchOpen Access14 Aug 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-10
Non-invasive measurement of leaf water content and pressure–volume curves using terahertz radiation

Ran Li
Yaojie Lu
Andrew J. Lee
ResearchOpen Access03 Dec 2020
Scientific Reports

Volume: 10, P: 1-14
Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis

Stefan Schefczyk
Xufeng Luo
Ruth Broering
ResearchOpen Access20 Dec 2023
Scientific Reports

Volume: 13, P: 1-14
Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

Chao Gao
Cuiting Peng
Yuquan Wei
ResearchOpen Access13 Jul 2016
Scientific Reports

Volume: 6, P: 1-9