Nature Search

Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

Mina D Marmor
Yosef Yarden
Reviews15 Mar 2004
Oncogene

Volume: 23, P: 2057-2070
A module of negative feedback regulators defines growth factor signaling

Ido Amit
Ami Citri
Yosef Yarden
Research25 Feb 2007
Nature Genetics

Volume: 39, P: 503-512
Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

Semir Beyaz
Miyeko D. Mana
Ömer H. Yilmaz
Amendments and Corrections30 May 2018
Nature

Volume: 560, P: E26
Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8⁺ T cell activation and limit responsiveness to immunotherapy in mice

Cancer-associated fibroblasts (CAFs) are abundant in the stroma of pancreatic ductal carcinoma (PDAC) tumors. In this study, the authors demonstrate using human samples and mouse models that senescent CAFs impair CD8⁺ T cell responses and may contribute to poor responsiveness to immunotherapy in PDAC.

Benjamin Assouline
Rachel Kahn
Ittai Ben-Porath
ResearchOpen Access22 Jul 2024
Nature Communications

Volume: 15, P: 1-16
Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains

M Sundvall
L Peri
K Elenius
Research07 May 2007
Oncogene

Volume: 26, P: 6905-6914
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling

K Shtiegman
B S Kochupurakkal
Y Yarden
Research07 May 2007
Oncogene

Volume: 26, P: 6968-6978
Against storytelling of scientific results

Yarden Katz
Correspondence30 Oct 2013
Nature Methods

Volume: 10, P: 1045
A single-cell survey of the small intestinal epithelium

Profiling of 53,193 individual epithelial cells from the mouse small intestine identifies previously unknown cell subtypes and corresponding gene markers, providing insight into gut homeostasis and response to pathogens.

Adam L. Haber
Moshe Biton
Aviv Regev
Research08 Nov 2017
Nature

Volume: 551, P: 333-339
Transformation of the intestinal epithelium by the MSI2 RNA-binding protein

In mammals there are two Musashi proteins, MSI1 and MSI2, orthologues of the Drosophila protein, with roles in asymmetric stem cell division and cell fate determination. Here the authors report new functions for MSI2 in colorectal cancer using in vitro loss of function and in vivoectopic overexpression.

Shan Wang
Ning Li
Christopher J. Lengner
Research16 Mar 2015
Nature Communications

Volume: 6, P: 1-15
Modeling ductal carcinoma in situ: a HER2–Notch3 collaboration enables luminal filling

C-R Pradeep
W J Köstler
Y Yarden
Research11 Jul 2011
Oncogene

Volume: 31, P: 907-917
Analysis and design of RNA sequencing experiments for identifying isoform regulation

The mixture of isoforms model (MISO) assesses the confidence in estimates of the abundance of spliced exons or isoforms from paired-end RNA-seq data and detects their differential expression.

Yarden Katz
Eric T Wang
Christopher B Burge
Research07 Nov 2010
Nature Methods

Volume: 7, P: 1009-1015
Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

Gal Twito
Faiza Amterat Abu Abayed
Aeid Igbaria
ResearchOpen Access21 Oct 2025
Oncogene

Volume: 44, P: 4565-4575
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

A high-fat diet increases the number of intestinal stem cells in mammals, both in vivo and in intestinal organoids; a pathway that involves PPAR-δ confers organoid-initiating capacity to non-stem cells and induces them to form in vivo tumours after loss of the Apc tumour suppressor.

Semir Beyaz
Miyeko D. Mana
Ömer H. Yilmaz
Research02 Mar 2016
Nature

Volume: 531, P: 53-58
A reciprocal tensin-3–cten switch mediates EGF-driven mammary cell migration

Menachem Katz
Ido Amit
Yosef Yarden
Research22 Jul 2007
Nature Cell Biology

Volume: 9, P: 961-969
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

Albert W Cheng
Haoyi Wang
Rudolf Jaenisch
ResearchOpen Access27 Aug 2013
Cell Research

Volume: 23, P: 1163-1171
High-intensity interval training attenuates development of autoimmune encephalomyelitis solely by systemic immunomodulation

Yehuda Goldberg
Shir Segal
Ofira Einstein
ResearchOpen Access02 Oct 2023
Scientific Reports

Volume: 13, P: 1-12
EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

G Pines
P H Huang
Y Yarden
Research02 Aug 2010
Oncogene

Volume: 29, P: 5850-5860

Search

Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

A module of negative feedback regulators defines growth factor signaling

Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8⁺ T cell activation and limit responsiveness to immunotherapy in mice

Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling

Against storytelling of scientific results

A single-cell survey of the small intestinal epithelium

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein

Modeling ductal carcinoma in situ: a HER2–Notch3 collaboration enables luminal filling

Analysis and design of RNA sequencing experiments for identifying isoform regulation

Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

A reciprocal tensin-3–cten switch mediates EGF-driven mammary cell migration

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

High-intensity interval training attenuates development of autoimmune encephalomyelitis solely by systemic immunomodulation

EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

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