Larionova et al. identify a mechanism by which acidification of the tumour microenvironment within the glioblastoma core induces the generation of an alternative splice isoform of ribosomal protein RPL22L1, which regulates cell stemness and increases tumour heterogeneity.
- Tatyana D. Larionova
- Soniya Bastola
- Marat S. Pavlyukov