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Nature Biomedical Engineering (3)
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Showing 1–10 of 10 results

Advanced filters: Author: Yash Agarwal Clear advanced filters

Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains

Khloe S. Gordon
Taeyoon Kyung
Michael E. Birnbaum
Amendments and Corrections03 Feb 2023
Nature Biomedical Engineering

Volume: 7, P: 599-602
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains

Screening a large barcoded library of unique CD19-specific chimaeric antigen receptors with diverse intracellular domains allows for the discovery of receptors that elicit enhanced antitumoural functions.

Khloe S. Gordon
Taeyoon Kyung
Michael E. Birnbaum
Research16 Jun 2022
Nature Biomedical Engineering

Volume: 6, P: 855-866
Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.

Pragya D. Yadav
Raches Ella
Balram Bhargava
ResearchOpen Access02 Mar 2021
Nature Communications

Volume: 12, P: 1-11
High-performance chemical- and light-inducible recombinases in mammalian cells and mice

The availability of high performance recombinases with low basal activity and high dynamic range is limited. Here the authors present a library of over 20 orthogonal split recombinases that can be induced by small molecules, light and temperature in vivo.

Benjamin H. Weinberg
Jang Hwan Cho
Wilson W. Wong
ResearchOpen Access24 Oct 2019
Nature Communications

Volume: 10, P: 1-10
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

The intratumoural injection of recombinantly expressed cytokines bound tightly to the common vaccine adjuvant aluminium hydroxide leads to weeks-long retention of the cytokines in the tumours with minimal side effects, as shown in multiple syngeneic mouse models.

Yash Agarwal
Lauren E. Milling
K. Dane Wittrup
Research10 Jan 2022
Nature Biomedical Engineering

Volume: 6, P: 129-143
Engineered immunogen binding to alum adjuvant enhances humoral immunity

Alum coupled to protein immunogens via site-specific phosphoserine-containing linkers enhances long-lived B cell responses and can selectively direct antibodies toward protective neutralizing epitopes.

Tyson J. Moyer
Yu Kato
Darrell J. Irvine
Research17 Feb 2020
Nature Medicine

Volume: 26, P: 430-440
Development of humanized mouse and rat models with full-thickness human skin and autologous immune cells

Yash Agarwal
Cole Beatty
Moses Bility
ResearchOpen Access03 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

Tyson J. Moyer
Yu Kato
Darrell J. Irvine
Amendments and Corrections16 Apr 2020
Nature Medicine

Volume: 26, P: 804
Author Correction: Development of humanized mouse and rat models with full-thickness human skin and autologous immune cells

Yash Agarwal
Cole Beatty
Moses Bility
Amendments and CorrectionsOpen Access14 Sept 2021
Scientific Reports

Volume: 11, P: 1
Optimization of an alum-anchored clinical HIV vaccine candidate

Kristen A. Rodrigues
Christopher A. Cottrell
Darrell J. Irvine
ResearchOpen Access12 Aug 2023
npj Vaccines

Volume: 8, P: 1-14