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Nature Microbiology (1)

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ATG5 suppresses type I IFN-dependent neutrophil effector functions during Mycobacterium tuberculosis infection in mice

ATG5 expression in neutrophils counters type I interferon signalling and downstream activation of neutrophil swarming and NET release to limit disease severity during Mycobacterium tuberculosis infection.

Rachel L. Kinsella
Chanchal Sur Chowdhury
Christina L. Stallings
Research15 May 2025
Nature Microbiology

Volume: 10, P: 1323-1339

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ATG5 suppresses type I IFN-dependent neutrophil effector functions during Mycobacterium tuberculosis infection in mice

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