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Showing 1–7 of 7 results

Advanced filters: Author: Yaxian Cheng Clear advanced filters

Compact RNA editors with natural miniature Cas13j nucleases

Li, Cheng, Yu and colleagues have discovered a Cas13j family, including the compact and highly efficient LepCas13j (529 aa) and ChiCas13j (424 aa), with promising applications in RNA editing in vivo.

Guo Li
Yaxian Cheng
Yuan Yao
Research19 Sept 2024
Nature Chemical Biology

Volume: 21, P: 280-290
Correction: Corrigendum: Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways

Xiaoyong Qiao
Ying Nie
Liangzhi Xu
Amendments and CorrectionsOpen Access15 Feb 2016
Scientific Reports

Volume: 6, P: 1
O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth

Post-translational modifications of phosphoglycerate kinase 1 (PGK1), a glycoytic enzyme, contribute to cancer progression. Here, the authors show that PGK1 is O-GlcNAcylated at T255, which induces its translocation into mitochondria to suppress the tricarboxylic acid cycle for colorectal cancer growth.

Hao Nie
Haixing Ju
Wen Yi
ResearchOpen Access07 Jan 2020
Nature Communications

Volume: 11, P: 1-14
Oncometabolite D-2-hydroxyglutarate—dependent metabolic reprogramming induces skeletal muscle atrophy during cancer cachexia

IDH1 mutation mediated D2HG accumulation contributes to the progression of cancer cachexia and muscle atrophy. IDH1 inhibitor ivosidenib delayed the progression of cancer cachexia in murine GL261 glioma model and CT26 colorectal carcinoma models.

Xinting Zhu
Juan Hao
Quanjun Yang
ResearchOpen Access23 Sept 2023
Communications Biology

Volume: 6, P: 1-19
Duplication and transcriptional divergence of three Kunitz protease inhibitor genes that modulate insect and pathogen defenses in tea plant (Camellia sinensis)

Junyan Zhu
Yaxian He
Chaoling Wei
ResearchOpen Access15 Nov 2019
Horticulture Research

Volume: 6, P: 1-12
Hepcidin depending on astrocytic NEO1 ameliorates blood-brain barrier dysfunction after subarachnoid hemorrhage

Boyang Wei
Wenchao Liu
Xifeng Li
ResearchOpen Access07 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-16
Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways

Xiaoyong Qiao
Ying Nie
Liangzhi Xu
ResearchOpen Access07 Jan 2016
Scientific Reports

Volume: 6, P: 1-12