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Showing 1–27 of 27 results
Advanced filters: Author: Yehuda Shoenfeld Clear advanced filters
  • Neuropsychiatric manifestations are present in approximately 70% of patients with systemic lupus erythematosus, and are often associated with a poor prognosis. In this Viewpoint, Dr Strous and Dr Shoenfeld discuss the potential role for autoimmune factors in contributing to neuropsychiatric expressions via direct and indirect autoantibody-induced neuronal damage.

    • Rael D Strous
    • Yehuda Shoenfeld
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 3, P: 592-593
  • Vitamin D is known to have many complex roles in human health-notably in the maintenance of immune homeostasis. In this Review Prof. Shoenfeld and colleagues explore the relationship between skin pigmentation and therefore vitamin D synthesis, with the incidence of autoimmune disease.

    • Netta Shoenfeld
    • Howard Amital
    • Yehuda Shoenfeld
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 5, P: 99-105
  • COVID-19, similarly to systemic autoimmune diseases, is characterised by the presence of autoantibodies. Authors show here that the abundance and network signature of autoantibodies targeting G protein-coupled receptors and RAS-related proteins are altered in COVID-19 patients, and the level of disruption marks clinical severity.

    • Otavio Cabral-Marques
    • Gilad Halpert
    • Yehuda Shoenfeld
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12
  • Cigarette smoking, in combination with genetic factors, creates a significant risk of developing systemic lupus erythematosus and rheumatoid arthritis, and can affect both the course and outcome of these rheumatic diseases. Also outlined in this article are the potential mechanisms by which smoking modulates the immune system.

    • Michal Harel-Meir
    • Yaniv Sherer
    • Yehuda Shoenfeld
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 3, P: 707-715
  • Vaccines are vital for protecting us against infectious diseases, but they have also been linked with the development of autoimmunity. In this article, the authors discuss the causal and temporal interactions between vaccines and autoimmune phenomena, and possible mechanisms by which different components of vaccines might induce autoimmune disease.

    • Nancy Agmon-Levin
    • Ziv Paz
    • Yehuda Shoenfeld
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 648-652
  • Pattern recognition molecules belonging to the innate immune response participate in the clearance of apoptotic cells. Among these molecules are the collectins C1q and mannose-binding lectin, and the pentraxins C-reactive protein, serum amyloid P component, and pentraxin 3. This Review discusses the prevalence, actions and clinical significance of these molecules in autoimmune conditions.

    • Martine Szyper Kravitz
    • Yehuda Shoenfeld
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 2, P: 481-490
  • Evolving understanding of the role of helminths in the pathogenesis of autoimmunity has led to the development of novel therapeutic interventions that are showing promise in patients with immune-mediated diseases. Meanwhile, studies in animal models of arthritis suggest that these new products might also be applicable in autoimmune rheumatic disease.

    • Dana Ben-Ami Shor
    • Yehuda Shoenfeld
    News & Views
    Nature Reviews Rheumatology
    Volume: 9, P: 138-140
  • Antiphospholipid syndrome is an autoimmune disease associated with a variety of symptoms, including thrombosis and obstetrical complications. This Primer provides an update on the epidemiology, pathogenesis, diagnosis and therapeutic aspects and offers an outlook on future research topics.

    • Karen Schreiber
    • Savino Sciascia
    • Beverley J. Hunt
    Reviews
    Nature Reviews Disease Primers
    Volume: 4, P: 1-20
  • Rheumatoid diseases such as rheumatoid arthritis are associated with accelerated atherosclerosis, increased cardiovascular morbidity and mortality. The early signs of cardiovascular disease therefore need to be recognized in these patients so that effective cardiovascular protection can be introduced. In this Review the authors discuss validated techniques that are currently available to determine subclinical atherosclerosis in patients with rheumatic conditions.

    • György Kerekes
    • Pál Soltész
    • Zoltán Szekanecz
    Reviews
    Nature Reviews Rheumatology
    Volume: 8, P: 224-234
  • Patients with autoimmune rheumatic diseases are at a high risk of developing premature atherosclerosis and subsequent cardiovascular disease. This Review discusses the role of the immune system in this process and highlights potential ways in which the development of atherosclerosis can be immunomodulated in experimental models.

    • Yaniv Sherer
    • Yehuda Shoenfeld
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 2, P: 99-106
  • In this article, the authors review the global burden of autoimmune rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren's syndrome and ankylosing spondylitis, across regions and ethnic populations, and discuss how evidence from geoepidemiological studies could provide insights into the genetic and environmental determinants of these conditions.

    • Yinon Shapira
    • Nancy Agmon-Levin
    • Yehuda Shoenfeld
    Reviews
    Nature Reviews Rheumatology
    Volume: 6, P: 468-476
  • Components of the human diet can have a profound effect on the way in which the human body responds to its environment. In this Review, the authors discuss several common dietary factors, outlining their effects on the development and progression of autoimmune rheumatic diseases via a common factor — the microbiome.

    • Shani Dahan
    • Yahel Segal
    • Yehuda Shoenfeld
    Reviews
    Nature Reviews Rheumatology
    Volume: 13, P: 348-358
  • Therapeutic application of cannabis remains controversial despite evidence of pain-relieving functions, particularly for rheumatic diseases. However, whether cannabis can also be used as an immunomodulatory therapeutic agent needs to be counterbalanced by risk assessment for adverse effects.

    • Daphna Katz-Talmor
    • Itay Katz
    • Yehuda Shoenfeld
    Reviews
    Nature Reviews Rheumatology
    Volume: 14, P: 488-498
    • Shahar Shelly
    • Nancy Agmon-Levin
    • Yehuda Shoenfeld
    Reviews
    Cellular & Molecular Immunology
    Volume: 8, P: 199-202