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Advanced filters: Author: Yemima R. Butler Clear advanced filters

  • Butler et al. selected disulfide bond-free nanobodies to target α-synuclein fibrils. Nanobody PFFNB2 was shown to disaggregate α-synuclein fibrils in vitro and inhibit α-synuclein pathology development in neuron cultures and mouse models.

    • Yemima R. Butler
    • Yuqing Liu
    • Wenjing Wang
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13