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Showing 1–2 of 2 results
Advanced filters: Author: Yeong-Geun Lee Clear advanced filters

  • Kim et al. show that several Streptococcus species improve the structure and barrier function of human skin. They find that Streptococcus-secreted spermidine accelerates the recovery of skin structure and barrier function by increasing collagen and lipid synthesis in aged cells. This study suggests the role of skin microbiome for anti-aging.

    • Gihyeon Kim
    • Misun Kim
    • Dong-Geol Lee
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-11

  • Kim et al. use RNAseq of two watermelons to select candidate genes coding for enzymes that catalyze modifications of cucurbitacins. They characterise four of the 16 candidate enzymes (3 different acetyltransferases and one UDP-glucosyltransferase) by HPLC, LC-MS, NMR, and in vitro enzymatic assay. They further show with in vivo assay in Drosophila, that acetylation of cucurbitacin increases neuronal activity in insects.

    • Young-Cheon Kim
    • Daeun Choi
    • Sanghyeob Lee
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-11